Definition of p53
: a tumor suppressor gene that in an inactivated form tends to be associated with a high risk of certain cancers
Recent Examples of p53 from the Web
The researchers put human BRAF and P53 genes in every melanocyte, the pigmented skin cells, of the fish.
Studies published in October say elephant DNA holds 20 copies of p53, an important tumor-suppressing gene, compared to only one in the DNA of humans and other mammals.
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Origin and Etymology of p53
from p53, the protein made by the gene, from protein + 53, the gene's molecular weight
First Known Use: 1990See Words from the same year
Medical Definition of p53
: a tumor suppressor gene that in a defective form tends to be associated with a high risk of certain cancers (as of the colon, lung, and breast)
Learn More about p53
Britannica.com: Encyclopedia article about p53
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