jaded

overfatigued, overtaxed, overworked

broken-down, run-down

debilitated, enervate, enervated, enfeebled, sapped, weakened

drowsy, heavy, sleepy

lethargic, sluggish

apathetic, disinterested, uninterested

glutted, sated, satiated, surfeited

dejected, demoralized, discouraged, disheartened, dispirited

beat, burned-out (or burnt-out), bushed, done in, drained, enervated, exhausted, fatigued, limp, played out, tuckered (out), worn-out

annoyed, exasperated, frustrated, irritated

disgusted, nauseated, repulsed

blasé (also blase), world-weary