retrovirus

noun

ret·ro·vi·rus | \ ˈre-trō-ˌvī-rəs

Definition of retrovirus

: any of a family (Retroviridae) of single-stranded RNA viruses that produce reverse transcriptase by means of which DNA is produced using their RNA as a template and incorporated into the genome of infected cells, that are often tumorigenic, and that include the lentiviruses (such as the HIVs) and the causative agent of Rous sarcoma

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Researchers knew retroviruses—which transcribe their RNA genome into DNA and integrate it into a host cell's genome—existed in animals. — Kai Kupferschmidt, Science | AAAS, "Scientists are declaring war against a leukemia-causing virus that has infected millions," 23 May 2018 Feline leukemia, a usually fatal cancer caused by a retrovirus, spreads from cat to cat via saliva, when the animals lick, bite, or groom one another. — Dr. Rob Sharp, Country Living, "Does my Indoor Cat Need Feline Leukemia Vaccine?," 28 June 2010 And in lab experiments, these porcine endogenous retroviruses (PERVs) tended to leap from pig to human cells. — Jonathon Keats, Discover Magazine, "Pig Cells That Won’t Go Retro," 24 Jan. 2018 The team also led the development of retroviruses as vectors to deliver DNA for gene therapy. — Meredith Wadman, Science | AAAS, "Famed cancer biologist allegedly sexually harassed women for decades," 26 Apr. 2018 Gandy cited research that identified high levels of retrovirus in the brains of patients with Amyotrophic Lateral Sclerosis (ALS, or Lou Gehrig’s Disease). — Melissa Healy, latimes.com, "Surprising discovery about viruses and Alzheimer’s disease could open new avenues for treatment," 22 June 2018 Some overlapped with regions of the genome that seem to belong to retroviruses that invaded our ancestors’ genomes; others belong to other repetitive stretches, which are rarely translated into proteins. — Cassandra Willyard, Scientific American, "New Human Gene Tally Reignites Debate," 19 June 2018 The discovery of the first human retrovirus in 1980 was a minor scientific sensation. — Kai Kupferschmidt, Science | AAAS, "Scientists are declaring war against a leukemia-causing virus that has infected millions," 23 May 2018 First of all, HIV is a retrovirus, a type of virus that rarely infects humans. — Adam Rogers, WIRED, "The Man Who Says Science Blew Its Best Shot at an AIDS Vaccine," 1 June 2018

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