Definition of first-linenext
as in selected
singled out from a number or group as more to one's liking surgery is usually not considered a first-line treatment for this type of cancer

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Example Sentences

Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Recent Examples of first-line Even the current first-line oral treatment, fexinidazole, must be taken for 10 days and comes with severe side effects such as nausea, vomiting and heart-rhythm disturbances. Fran Kritz, NPR, 16 Mar. 2026 That may help researchers identify which patient populations should get immunotherapy as a first-line treatment. Kerry Breen, CBS News, 14 Mar. 2026 The American College of Physicians recommends CBT-I as the first-line treatment for chronic insomnia. Allison Palmer march 4, Charlotte Observer, 4 Mar. 2026 Now, in a new paper in the journal Cell Press Blue, researchers report that if the tissue’s first-line defenses fail, then what could have been a mild infection spirals out of control. Veronique Greenwood, Time, 27 Feb. 2026 See All Example Sentences for first-line
Recent Examples of Synonyms for first-line
Adjective
  • The selected artist will be notified by early October.
    News Release, San Diego Union-Tribune, 21 Mar. 2026
  • The gist, however, seems to be that extra-terrestrials make contact with a selected few, before promising to go public to the entire world — good luck dealing with the ramifications of that one, human race!
    Richard Edwards, Space.com, 31 Dec. 2025
Adjective
  • Since select streamers are offering free trials and limited-time discounts, viewers can watch the latest episodes of Kara Swisher Wants to Live Forever at no cost; keep reading to learn more about each option.
    Erin Lassner, HollywoodReporter, 11 Apr. 2026
  • The food tour company also offers small group culinary tours that include cooking courses taking place on select dates or that can be scheduled at any time.
    Beth Luberecki, USA Today, 11 Apr. 2026
Adjective
  • Style it by the edge of your sofa to add bonus space for your morning coffee or evening snacks, or use it by a window in your entryway, bedroom, or kitchen as a pedestal table to show off your favorite houseplants.
    Caley Sturgill, Southern Living, 16 Apr. 2026
  • Gemini in Chrome is rolling out a new feature called Skills to save and reuse your favorite prompts.
    Jibin Joseph, PC Magazine, 15 Apr. 2026
Adjective
  • Flats used to be the preferred method, but Faust doesn’t think that’s in the berry’s best interest.
    Stacey Lastoe, Southern Living, 20 Apr. 2026
  • OpenAI memo criticizes Anthropic watch now Choose CNBC as your preferred source on Google and never miss a moment from the most trusted name in business news.
    Ashley Capoot, CNBC, 20 Apr. 2026
Adjective
  • Periods of technological transformation often coincide with capital over-concentration, valuation compression outside the favored theme, and eventual normalization.
    Matt Witheiler, Fortune, 4 Apr. 2026
  • The Washington Consensus was traditionally wary of developing countries picking winners and losers, erecting trade barriers and subsidizing favored industries.
    Editorial Board, Washington Post, 24 Mar. 2026

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Cite this Entry

“First-line.” Merriam-Webster.com Thesaurus, Merriam-Webster, https://www.merriam-webster.com/thesaurus/first-line. Accessed 21 Apr. 2026.

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