FIRST-LINE Synonyms: 24 Similar and Opposite Words

first-line

adjective

ˈfərst-ˈlīn

as in selected

singled out from a number or group as more to one's liking surgery is usually not considered a first-line treatment for this type of cancer

Synonyms & Similar Words

Relevance

Antonyms & Near Antonyms

Example Sentences

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Recent Examples of first-line According to Ingber, first-line therapy often includes dietary and behavioral modifications, along with pelvic floor physical therapy. —

Lauryn Higgins, Flow Space, 1 May 2026 Brock Faber had the first goal for the Wild, who were again without first-line right wing Mats Zuccarello due to an upper-body injury that occurred in Game 1 and felt his absence on their flagging power play. —

CBS News, 26 Apr. 2026 What To Consider Instead For chronic insomnia, the American Academy of Sleep Medicine recommends CBT-I (Cognitive Behavioral Therapy for Insomnia) as a first-line treatment, ahead of supplements or medication. —

Allison Palmer, Sacbee.com, 16 Apr. 2026 For chronic insomnia, the American Academy of Sleep Medicine recommends Cognitive Behavioral Therapy for Insomnia as the first-line treatment, ahead of any supplement or medication. —

Allison Palmer, Fort Worth Star-Telegram, 15 Apr. 2026 See All Example Sentences for first-line

Recent Examples of Synonyms for first-line

Adjective

Sticking with the manufacturer’s pre-selected stain and paint options is a great way to cut back on unnecessary costs.

— Cori Sears, The Spruce, 28 Apr. 2026
The selected artist will be notified by early October.

— News Release, San Diego Union-Tribune, 21 Mar. 2026