How to Use first-line in a Sentence

first-line

adjective

• That’s the equivalent of a low-end first-line rate.
  — Harman Dayal, New York Times, 24 Dec. 2025
• Her main concern is when they are offered as a first-line solution.
  — Alyssa Goldberg, USA Today, 10 Sep. 2025
• Get your ground truth from data, facts, and first-line supervisors.
  — George Bradt, Forbes.com, 26 May 2025
• And they are never used as a first-line therapy, only as a last resort.
  — Dr. Sanjay Gupta, CNN Money, 2 Sep. 2025
• Reinhart, a first-line forward, has four goals and seven assists in the playoffs this year.
  — Adam Lichtenstein, Sun Sentinel, 24 May 2025
• The drug is being positioned as a first-line treatment option.
  — Justin Zacks, CNBC, 4 June 2026
• There’s more consistent offence in his game (eight points in 10 games) as their new first-line right winger.
  — Joshua Kloke, The Athletic, 1 Jan. 2025
• Minten, 21, took some first-line shifts with David Pastrnak.
  — Fluto Shinzawa, New York Times, 8 May 2026
• Larkin owes his employer first-line performance for five more seasons.
  — Fluto Shinzawa, New York Times, 5 June 2026
• And just as with Bessie and Bluebell, first-line treatment doesn’t always start with a pill.
  — Pat Beall, Sun Sentinel, 12 June 2026
• But there’s a clear lack of true first-line-caliber drivers, even if Pettersson bounces back.
  — James Mirtle, New York Times, 8 Oct. 2025
• Then the Wings lost Vrana and first-line winger Tyler Bertuzzi, forcing some new looks.
  — Helene St. James, Detroit Free Press, 28 Apr. 2023
• Corticosteroids are one of the first-line treatments for lupus.
  — Anne Harding, Health, 19 Apr. 2023
• Zidesamtinib is also being explored as a first-line treatment.
  — Meghana Keshavan, STAT, 23 July 2026
• His play has electrified this franchise in a big way and helps make up for the fact that this team doesn’t have an elite first-line center.
  — Shayna Goldman, New York Times, 9 Oct. 2025
• The study authors aren’t the only ones who advise against Benadryl as a first-line defense.
  — Cathy Nelson, Health, 16 July 2025
• Anybody can see the Wild are a scoring winger or first-line center away from true contender status.
  — Michael Russo, New York Times, 14 Jan. 2026
• Colorado has added a first-line wing, two bottom-six forwards, a top-five defenseman and two goaltenders.
  — Corey Masisak, The Denver Post, 3 Mar. 2025
• It has been used as a first-line treatment in Canada and parts and Europe for more than 40 years.
  — Claire Bugos, Verywell Health, 8 May 2024
• While beta-blockers used to be a first-line treatment for hypertension, their role has changed in recent years.
  — Ayesha Gulzar, Verywell Health, 18 July 2024
• Metformin is a first-line treatment for type 2 diabetes in adults and children aged 10 and above.
  — Nick Blackmer, Verywell Health, 15 Apr. 2024
• Rossi isn’t a traditional first-line center in terms of production or play-driving.
  — The Athletic Nhl, New York Times, 29 Sep. 2025
• That’s a big step up from what’s expected of an $8 million forward, which is to provide low-end, first-line value.
  — Dom Luszczyszyn, New York Times, 29 July 2025
• Among the drugs in shortage is carboplatin, a chemotherapy agent used as a first-line treatment for a number of cancers.
  — Marina Kopf, NBC News, 26 May 2023
• This slows down the progression of kidney disease and is typically used as a first-line treatment.
  — David Hampton, Verywell Health, 27 Aug. 2025
• The medications can be used along previous first-line treatments for migraine.
  — Syeda Khaula Saad, Verywell Health, 3 Apr. 2024
• This could be an intriguing buy-low opportunity for a player with star, first-line upside.
  — Harman Dayal, New York Times, 30 May 2025
• Until now, levodopa has been the standard first-line treatment for Parkinson’s patients.
  — Melissa Rudy, FOXNews.com, 18 Apr. 2025
• That’s a big reason Blackhawks coach Jeff Blashill has kept him at first-line center despite the drought.
  — Mark Lazerus, New York Times, 8 Jan. 2026
• This is the first first-line FDA approval for a drug treating this cancer in over 20 years.
  — Katie Jennings, Forbes, 19 Apr. 2023