How to Use first-line in a Sentence

first-line

adjective

• Then the Wings lost Vrana and first-line winger Tyler Bertuzzi, forcing some new looks.
  — Helene St. James, Detroit Free Press, 28 Apr. 2023
• This is the first first-line FDA approval for a drug treating this cancer in over 20 years.
  — Katie Jennings, Forbes, 19 Apr. 2023
• It has been used as a first-line treatment in Canada and parts and Europe for more than 40 years.
  — Claire Bugos, Verywell Health, 8 May 2024
• The over-the-counter analgesic, sold as Tylenol or Panadol among other brand names, is the standard, first-line treatment for pain and fever.
  — New Atlas, 15 Dec. 2024
• There’s more consistent offence in his game (eight points in 10 games) as their new first-line right winger.
  — Joshua Kloke, The Athletic, 1 Jan. 2025
• The study authors aren’t the only ones who advise against Benadryl as a first-line defense.
  — Cathy Nelson, Health, 16 July 2025
• Reinhart, a first-line forward, has four goals and seven assists in the playoffs this year.
  — Adam Lichtenstein, Sun Sentinel, 24 May 2025
• Metformin is a first-line treatment for type 2 diabetes in adults and children aged 10 and above.
  — Nick Blackmer, Verywell Health, 15 Apr. 2024
• Nearly 70% of adults in the U.S. use over-the-counter medications as a first-line response for treating cold and flu symptoms.
  — Macarius Mwinisungee Donneyong, Fortune Well, 21 Apr. 2023
• Since the 1930s, EEGs have been the first-line method for recording the sleeping brain’s electrical activity.
  — Lucy Tu, Smithsonian Magazine, 24 Mar. 2023
• Get your ground truth from data, facts, and first-line supervisors.
  — George Bradt, Forbes.com, 26 May 2025
• Corticosteroids are one of the first-line treatments for lupus.
  — Anne Harding, Health, 19 Apr. 2023
• That’s a big step up from what’s expected of an $8 million forward, which is to provide low-end, first-line value.
  — Dom Luszczyszyn, New York Times, 29 July 2025
• The 29-year-old is a dynamic top-six forward with first-line talent and a second-line history.
  — Murat Ates, The Athletic, 20 Feb. 2025
• Colorado has added a first-line wing, two bottom-six forwards, a top-five defenseman and two goaltenders.
  — Corey Masisak, The Denver Post, 3 Mar. 2025
• Among the drugs in shortage is carboplatin, a chemotherapy agent used as a first-line treatment for a number of cancers.
  — Marina Kopf, NBC News, 26 May 2023
• Police also used a liquid known as Bluestar that is meant to be a first-line method of picking up blood stains not visible to the human eye.
  — Jessica Garrison, Los Angeles Times, 1 June 2024
• While beta-blockers used to be a first-line treatment for hypertension, their role has changed in recent years.
  — Ayesha Gulzar, Verywell Health, 18 July 2024
• Until now, levodopa has been the standard first-line treatment for Parkinson’s patients.
  — Melissa Rudy, FOXNews.com, 18 Apr. 2025
• More comfortable in the middle, but that he’s being asked to be first-line center at times says more about the organization’s needs.
  — Fluto Shinzawa, The Athletic, 7 Jan. 2025
• It’s considered the first-line treatment for tic disorders.
  — Kelly Burch Published, Verywell Health, 26 June 2025
• Hirsch said doctors in the U.S. would likely use the same first-line BV medications—metronidazole and clindamycin gel—to treat male partners.
  — Fran Kritz, Verywell Health, 12 Mar. 2025
• Therefore, using an enema as a first-line treatment for all types of constipation would be sort of like using an axe to cut a piece of cake.
  — Bruce Y. Lee, Forbes.com, 12 July 2025
• Suter is the sort of player teams win with, even if asking him to play first-line centre at the most difficult point in the regular season calendar might be a bridge too far.
  — Thomas Drance, The Athletic, 24 Mar. 2025
• Suter is the sort of player teams win with, even if asking him to play first-line centre at the most difficult point in the regular season calendar might be a bridge too far.
  — Thomas Drance, The Athletic, 24 Mar. 2025
• Clomid and letrozole are the first-line fertility treatments for people with PCOS.
  — Rachel Gurevich, Parents, 30 July 2024
• The first-line treatment for foot pain often involves resting your feet and wearing more supportive shoes, like sneakers.
  — Kelly Burch Published, Verywell Health, 14 July 2025
• When antihistamines, the standard first-line treatment, fail to provide relief, systemic therapies that work throughout the body are the next step.
  — New Atlas, 17 July 2025
• Providers first try first-line drugs, which are known to be the most effective (before the development of antimicrobial resistance) and the least toxic.
  — Erin Prater, Fortune Well, 17 Jan. 2024
• Anybody can see the Wild are a scoring winger or first-line center away from true contender status.
  — Michael Russo, New York Times, 14 Jan. 2026