first-line
adjective
: being the preferred, standard, or first choice
first-line treatment of tuberculosis
compare second-line
Examples of first-line in a Sentence
surgery is usually not considered a first-line treatment for this type of cancer
Recent Examples on the Web
Her main concern is when they are offered as a first-line solution.
—
Alyssa Goldberg, USA Today, 10 Sep. 2025
And they are never used as a first-line therapy, only as a last resort.
—Dr. Sanjay Gupta, CNN Money, 2 Sep. 2025
Sales of Abrysvo, the company’s RSV vaccine, surged 155% on uptake among adults and pregnant women, while cancer therapies such as Lorbrena saw a 48% rise in sales on stronger first-line use.
—John Buckingham, Forbes.com, 28 Aug. 2025
Overall, SSRIs are effective, widely used, and considered a first-line treatment for many mood and anxiety disorders when managed carefully by a doctor.
—Hannah Parry, MSNBC Newsweek, 28 Aug. 2025
See All Example Sentences for first-line
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Alyssa Goldberg, USA Today, 10 Sep. 2025
And they are never used as a first-line therapy, only as a last resort.
—Dr. Sanjay Gupta, CNN Money, 2 Sep. 2025
Sales of Abrysvo, the company’s RSV vaccine, surged 155% on uptake among adults and pregnant women, while cancer therapies such as Lorbrena saw a 48% rise in sales on stronger first-line use.
—John Buckingham, Forbes.com, 28 Aug. 2025
Overall, SSRIs are effective, widely used, and considered a first-line treatment for many mood and anxiety disorders when managed carefully by a doctor.
—Hannah Parry, MSNBC Newsweek, 28 Aug. 2025
See All Example Sentences for first-line
Cite this Entry
“First-line.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/first-line. Accessed 29 Sep. 2025.
Copy CitationMedical Definition
first-line
adjective
: being the preferred, standard, or first choice
first-line treatment of advanced breast cancer
compare second-line
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