second-line
adjective
sec·ond-line
ˈse-kᵊn(d)-ˈlīn 
: not being the usual or preferred choice
second-line drugs to treat tuberculosis
compare first-line
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“Second-line.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/second-line. Accessed 31 Oct. 2025.
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second-line
adjective
sec·ond-line
ˌsek-ᵊn(d)-ˌlīn
: being or using a drug that is not the usual or preferred choice compare first-line
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