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sec·ond-line | \ ˈse-kᵊn(d)-ˈlīn 
\
\Definition of second-line
: not being the usual or preferred choice
second-line drugs to treat tuberculosis — compare first-line
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More Definitions for second-line
second-line
adjectivesec·ond-line | \ ˌsek-ᵊn(d)-ˌlīn \
\Medical Definition of second-line
: being or using a drug that is not the usual or preferred choice — compare first-line
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The first known use of second-line was in 1969
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