annoy implies a wearing on the nerves by persistent petty unpleasantness.
their constant complaining annoys us
vex implies greater provocation and stronger disturbance and usually connotes anger but sometimes perplexity or anxiety.
vexed by her son's failure to clean his room
irk stresses difficulty in enduring and the resulting weariness or impatience of spirit.
careless waste irks the boss
bother suggests interference with comfort or peace of mind.
don't bother me while I'm reading
Examples of vex in a Sentence
This problem has vexed researchers for years.
We were vexed by the delay.
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Siblings are rich terrain for fiction precisely because they are so vexed—a pressure point where the imperative to create a singular hero meets the desire to imagine new forms of connection.—Christine Smallwood, Harpers Magazine, 24 Mar. 2026 Some feel vexed by a whole host of things, including style of play, fanbase, history, managers, players, owners, financial might or, in City’s case, the pending Premier League charges.—Caoimhe O'Neill, New York Times, 21 Mar. 2026 Drones cost a fraction of the weapons needed to shoot them down, a math problem that has vexed military planners for years.—Chris Boccia, ABC News, 12 Mar. 2026 In flashbacks, viewers learn why Dorothy (Amanda Righetti) left an 11-year-old Lucy (Savannah Lumar) in Kay’s care, and how Lucy and Kay’s codependency continually vexes Dorothy.—Aramide Tinubu, Variety, 10 Mar. 2026 See All Example Sentences for vex
Word History
Etymology
Middle English, from Anglo-French vexer, from Latin vexare to agitate, harry; probably akin to Latin vehere to convey — more at way