annoy implies a wearing on the nerves by persistent petty unpleasantness.
their constant complaining annoys us
vex implies greater provocation and stronger disturbance and usually connotes anger but sometimes perplexity or anxiety.
vexed by her son's failure to clean his room
irk stresses difficulty in enduring and the resulting weariness or impatience of spirit.
careless waste irks the boss
bother suggests interference with comfort or peace of mind.
don't bother me while I'm reading
Examples of vex in a Sentence
This problem has vexed researchers for years.
We were vexed by the delay.
Recent Examples on the Web
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The other is a savvy tactician whose game centers on commanding his fastball, vexing hitters with his splitter and working in a refined slider.—
Cody Stavenhagen,
New York Times,
26 July 2026 The next few weeks are going to be just as vexing, with Mercury in Cancer entering its post-shadow zone from July 23 to August 6.—
Lisa Stardust,
Vogue,
26 July 2026 In the meantime, the deadly encounter has reignited a contentious debate about body cameras, one that has long vexed local officials and pitted some of the city’s progressive groups against each other.—ABC News,
24 July 2026 Particulars matter Haiti observers warn that considering the country’s vexing history with electoral fraud, violence, problematic votes and post-election crises, the particulars of its electoral machinery do matter.—
Jacqueline Charles,
Miami Herald,
24 July 2026 See All Example Sentences for vex
Word History
Etymology
Middle English, from Anglo-French vexer, from Latin vexare to agitate, harry; probably akin to Latin vehere to convey — more at way