annoy implies a wearing on the nerves by persistent petty unpleasantness.
their constant complaining annoys us
vex implies greater provocation and stronger disturbance and usually connotes anger but sometimes perplexity or anxiety.
vexed by her son's failure to clean his room
irk stresses difficulty in enduring and the resulting weariness or impatience of spirit.
careless waste irks the boss
bother suggests interference with comfort or peace of mind.
don't bother me while I'm reading
Examples of vex in a Sentence
This problem has vexed researchers for years.
We were vexed by the delay.
Recent Examples on the Web
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Zinn in the years to come was vexed both morally and politically by the impersonality of the killing as a bombardier.—Literary Hub,
12 Aug. 2026 This scene among the pines and mountains of a small central Vermont town reveals how Plainfield, with a population of nearly 1,000 people, is finding a way to solve a problem vexing communities across the United States.—
Olivia Fletcher,
Christian Science Monitor,
11 Aug. 2026 Medical schools, though, are facing a vexing quandary over AI scribes.—
Lauren Chan,
STAT,
3 Aug. 2026 The other is a savvy tactician whose game centers on commanding his fastball, vexing hitters with his splitter and working in a refined slider.—
Cody Stavenhagen,
New York Times,
26 July 2026 See All Example Sentences for vex
Word History
Etymology
Middle English, from Anglo-French vexer, from Latin vexare to agitate, harry; probably akin to Latin vehere to convey — more at way