annoy implies a wearing on the nerves by persistent petty unpleasantness.
their constant complaining annoys us
vex implies greater provocation and stronger disturbance and usually connotes anger but sometimes perplexity or anxiety.
vexed by her son's failure to clean his room
irk stresses difficulty in enduring and the resulting weariness or impatience of spirit.
careless waste irks the boss
bother suggests interference with comfort or peace of mind.
don't bother me while I'm reading
Examples of vex in a Sentence
This problem has vexed researchers for years.
We were vexed by the delay.
Recent Examples on the Web
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As much as the parameter-less financial model of the modern major college athletic department vexes leaders, the realities of the transfer portal are a close second — because they are linked.—Mac Engel
april 23, Fort Worth Star-Telegram, 23 Apr. 2026 In a joint statement, the foreign ministers of both nations, which share the island of Hispaniola and a vexing history, announced that the Dominican Republic would restore commercial flights between Santo Domingo and Cap-Haïtien for the first time in over two years, beginning May 1.—Jacqueline Charles, Miami Herald, 21 Apr. 2026 The third-year wing said he’s been working closely with Brown to devise methods of vexing Tyrese Maxey, the Sixers’ most dangerous offensive threat.—Zack Cox, Boston Herald, 19 Apr. 2026 The question of how to make a business out of those connections has proven as vexing for Wang and Bluesky as for any number of earlier startups, and the community’s top users have been experimenting with a variety of ways to make money.—Ben Smith, semafor.com, 10 Apr. 2026 See All Example Sentences for vex
Word History
Etymology
Middle English, from Anglo-French vexer, from Latin vexare to agitate, harry; probably akin to Latin vehere to convey — more at way