annoy implies a wearing on the nerves by persistent petty unpleasantness.
their constant complaining annoys us
vex implies greater provocation and stronger disturbance and usually connotes anger but sometimes perplexity or anxiety.
vexed by her son's failure to clean his room
irk stresses difficulty in enduring and the resulting weariness or impatience of spirit.
careless waste irks the boss
bother suggests interference with comfort or peace of mind.
don't bother me while I'm reading
Examples of vex in a Sentence
This problem has vexed researchers for years.
We were vexed by the delay.
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In flashbacks, viewers learn why Dorothy (Amanda Righetti) left an 11-year-old Lucy (Savannah Lumar) in Kay’s care, and how Lucy and Kay’s codependency continually vexes Dorothy.—Aramide Tinubu, Variety, 10 Mar. 2026 Fortunately, Japan’s leadership in this often vexing but manageable environment is promising.—Arthur I. Cyr, Chicago Tribune, 10 Mar. 2026 Judge is not the first athlete to be vexed by the challenge.—Rustin Dodd, New York Times, 5 Mar. 2026 Dinner has been vexing people for a very long time.—Rafaela Jinich, The Atlantic, 5 Mar. 2026 See All Example Sentences for vex
Word History
Etymology
Middle English, from Anglo-French vexer, from Latin vexare to agitate, harry; probably akin to Latin vehere to convey — more at way