substitute

1 of 2

noun

sub·​sti·​tute ˈsəb-stə-ˌtüt 

-ˌtyüt

: a person or thing that takes the place or function of another

substitute adjective

substitute

2 of 2

verb

substituted; substituting

transitive verb

1

a

: to put or use in the place of another

b

: to introduce (an atom or group) as a substituent

also : to alter (something, such as a compound) by introduction of a substituent

a substituted benzene ring

2

: to take the place of : replace

intransitive verb

: to serve as a substitute

Synonyms

Noun

• replacement

Verb

• exchange
• swap
• trade
• change
• replace

Examples of substitute in a Sentence

Noun

you'll be getting a substitute until your regular teacher is feeling better

if you like, you can use nuts as a substitute for coconut in that recipe

Verb

One of our teachers is sick, so we need someone to substitute.

They substituted real candles with electric ones.

Recent Examples on the Web

Noun

Xylitol, a sweetener often used as a sugar substitute in these pops, reduces the growth of cavity-causing bacteria. —Angela Haupt, Time, 28 Oct. 2025

Combine them with water to use as an egg substitute in recipes. —Carrie Madormo, Verywell Health, 27 Oct. 2025

Verb

This article is for informational purposes only and does not substitute for professional medical advice. —Lyssanoel Frater, USA Today, 21 Oct. 2025

But this was the first of three Terence Fisher Frankenstein films to substitute the iconic Monster for an equivalent and ill-fated experiment; in this case, a paralysed hospital assistant Karl (Oscar Quitak) who agrees to have his brain transplanted into an able body (Michael Gwynn). —Rory Doherty, Vulture, 20 Oct. 2025

Word History

Etymology

Noun

Middle English, from Anglo-French substitut, from Latin substitutus, past participle of substituere to put in place of, from sub- + statuere to set up, place — more at statute

First Known Use

Noun

14th century, in the meaning defined above

Verb

15th century, in the meaning defined at transitive sense 1a

Phrases Containing substitute

• substitute teacher

Rhymes for substitute

• absolute
• arrowroot
• attribute
• bitterroot
• constitute
• convolute
• destitute
• disrepute
• dissolute
• execute
• institute
• involute

Kids Definition

substitute

1 of 2 noun

sub·​sti·​tute ˈsəb-stə-ˌt(y)üt 

: a person or thing that takes the place of another

substitute adjective

substitute

2 of 2 verb

substituted; substituting

1

: to put in the place of another : replace

2

: to serve as a substitute

substitution

ˌsəb-stə-ˈt(y)ü-shən

noun

Medical Definition

substitute

1 of 2 noun

sub·​sti·​tute ˈsəb-stə-ˌt(y)üt 

: a person or thing that takes the place or function of another

father and mother substitutes

substitute adjective

substitute

2 of 2 transitive verb

substituted; substituting

: to put or use in the place of another: as

a

: to introduce (an atom or group) as a substituent

b

: to alter (as a compound) by introduction of a substituent