substitute

1 of 2

noun

sub·​sti·​tute ˈsəb-stə-ˌtüt 

-ˌtyüt

: a person or thing that takes the place or function of another

substitute adjective

substitute

2 of 2

verb

substituted; substituting

transitive verb

1

a

: to put or use in the place of another

b

: to introduce (an atom or group) as a substituent

also : to alter (something, such as a compound) by introduction of a substituent

a substituted benzene ring

2

: to take the place of : replace

intransitive verb

: to serve as a substitute

Synonyms

Noun

• backup
• cover
• designated hitter
• fill-in
• locum tenens
• pinch hitter
• relief
• replacement
• reserve
• stand-in
• sub

Verb

• change
• commute
• exchange
• shift
• swap
• switch
• trade

Examples of substitute in a Sentence

Noun

you'll be getting a substitute until your regular teacher is feeling better

if you like, you can use nuts as a substitute for coconut in that recipe

Verb

One of our teachers is sick, so we need someone to substitute.

They substituted real candles with electric ones.

Recent Examples on the Web

Noun

If used mindfully, AI can be part of a modern intimacy toolkit, if not leveraged as a substitute for human connection. —Dominique Fluker, Essence, 15 May 2025

Here is Tim’s verdict, based on the lad’s 38 minutes as a substitute. —Phil Hay, New York Times, 15 May 2025

Verb

This article is for informational purposes only and does not substitute for professional medical advice. —Wyles Daniel, USA Today, 17 May 2025

Adoptees who have searched for information about their birth families and academics who have studied international adoption have long known of cases in which one child was substituted at the last minute for another—or of birth mothers who were coerced or tricked into relinquishing their children. —Time, 15 May 2025

Word History

Etymology

Noun

Middle English, from Anglo-French substitut, from Latin substitutus, past participle of substituere to put in place of, from sub- + statuere to set up, place — more at statute

First Known Use

Noun

14th century, in the meaning defined above

Verb

15th century, in the meaning defined at transitive sense 1a

Phrases Containing substitute

• substitute teacher

Rhymes for substitute

• absolute
• arrowroot
• attribute
• bitterroot
• constitute
• convolute
• destitute
• disrepute
• dissolute
• execute
• institute
• involute

Kids Definition

substitute

1 of 2 noun

sub·​sti·​tute ˈsəb-stə-ˌt(y)üt 

: a person or thing that takes the place of another

substitute adjective

substitute

2 of 2 verb

substituted; substituting

1

: to put in the place of another : replace

2

: to serve as a substitute

substitution

ˌsəb-stə-ˈt(y)ü-shən

noun

Medical Definition

substitute

1 of 2 noun

sub·​sti·​tute ˈsəb-stə-ˌt(y)üt 

: a person or thing that takes the place or function of another

father and mother substitutes

substitute adjective

substitute

2 of 2 transitive verb

substituted; substituting

: to put or use in the place of another: as

a

: to introduce (an atom or group) as a substituent

b

: to alter (as a compound) by introduction of a substituent