prebiotic

1 of 2

adjective

pre·​bi·​ot·​ic ˌprē-bī-ˈä-tik 

1

: of, relating to, or being chemical or environmental precursors of the origin of life

… it is possible that either the prebiotic molecules necessary for the evolution of life or the raw materials from which these molecules formed were brought to Earth by comet-like objects.

—Marcia Neugebauer

also : existing or occurring before the origin of life

… RNA is a chemically fragile molecule, unlikely to survive the harsh prebiotic conditions.

—Michael Egholm et al.

2

: of, relating to, or being a prebiotic

… next-generation probiotic microbes administered along with the appropriate prebiotic nutrients to nourish them.

—Michael Pollan

prebiotic

2 of 2

noun

: a substance and especially a carbohydrate (such as inulin) that is nearly or wholly indigestible and that when consumed (as in food) promotes the growth of beneficial bacteria in the digestive tract

Prebiotics are naturally found in certain fruits, vegetables, and herbs, including artichoke, asparagus, bananas, chicory, garlic, and onions.

—Andrew Weil

compare probiotic

Examples of prebiotic in a Sentence

Recent Examples on the Web

Adjective

Compared to prebiotic sodas, which often contain a specific prebiotic known as inulin but not much else, whole foods offer a much broader array of beneficial nutrients—including polyphenols. —Caroline Tien, SELF, 12 Dec. 2025

Nestlé unveiled a new protein shake in June with four grams of prebiotic fiber designed specifically to support the digestive health of adults on GLP-1 medications. —Laya Neelakandan, CNBC, 12 Dec. 2025

Noun

The fiber and prebiotics in the sweet potato are great for your gut. —Sheah Rarback, Miami Herald, 18 Dec. 2025

Compared to prebiotic sodas, which often contain a specific prebiotic known as inulin but not much else, whole foods offer a much broader array of beneficial nutrients—including polyphenols. —Caroline Tien, SELF, 12 Dec. 2025

Word History

Etymology

Adjective

pre- + biotic

First Known Use

Adjective

1954, in the meaning defined at sense 1

Noun

1995, in the meaning defined above

Rhymes for prebiotic

• abiotic
• aeronautic
• apoptotic
• asymptotic
• cyanotic
• eukaryotic
• idiotic
• meiotic
• patriotic
• probiotic
• prokaryotic
• semiotic

Medical Definition

prebiotic

1 of 2 adjective

pre·​bi·​ot·​ic

-bī-ˈät-ik

1

: of, relating to, or being chemical or environmental precursors of the origin of life

prebiotic molecules

also : existing or occurring before the origin of life

prebiotic conditions

2

: of, relating to, or being a prebiotic

Prebiotic agents included the oligosaccharides inulin, galactose, fructose, lactulose, and combinations of these nutrients.

—Josef Neu et al., The New England Journal of Medicine

prebiotically

-i-k(ə-)lē

adverb

prebiotic

2 of 2 noun

: a substance and especially a carbohydrate (such as inulin) that is nearly or wholly indigestible and that when consumed (as in food) promotes the growth of beneficial bacteria in the digestive tract compare probiotic