par·​ox·​e·​tine | \ pa-ˈräk-sə-ˌtēn How to pronounce paroxetine (audio) \

Definition of paroxetine

: a drug C19H20FNO3 that enhances serotonin activity and is usually administered in the form of its hydrochloride to treat depression

Examples of paroxetine in a Sentence

Recent Examples on the Web Withdrawal symptoms in people stopping depression medications of the class of paroxetine (Paxil) are common. Dr. Keith Roach, oregonlive, 13 May 2022 However, paroxetine tends to be the most difficult of these. Dr. Keith Roach, oregonlive, 13 May 2022 For women who are not good candidates for hormone therapy, there are a few non-hormonal treatments as well, says Dr. Streicher, including a low-dose form of the antidepressant paroxetine, which has been FDA-approved to treat hot flashes. Marisa Cohen, Good Housekeeping, 5 May 2022 Founded in 2019, Evernow offers telehealth patients hormone therapies including estradiol patches or pills, and SSRI paroxetine, used to treat hot flashes and night sweats. Emma Hinchliffe, Fortune, 6 Apr. 2022 The blood thinner warfarin is one example; so is oseltamivir, the key ingredient in the flu medication known in the US as Tamiflu; so is paroxetine, an antidepressant. Samanth Subramanian, Quartz, 6 Oct. 2021 Risk for the coronavirus was reduced in those who had a pneumococcal polysaccharide or influenza vaccine, or were on melatonin, paroxetine, or carvedilol, according to Clinic research. Julie Washington, cleveland, 16 June 2020 Those who take melatonin as an over-the-counter sleep aid, the heart medication carvedilol or the anti-depressant paroxetine are less likely to test positive than patients who don’t take those medications, the study suggested. Julie Washington, cleveland, 16 June 2020 Of the 11 antidepressants analyzed, mirtazapine (Remeron) caused the greatest weight gain, followed by paroxetine (Paxil). Andrea Alfano, Scientific American, 1 July 2015 See More

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'paroxetine.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

First Known Use of paroxetine

1977, in the meaning defined above

History and Etymology for paroxetine

perhaps from International Scientific Vocabulary par- (alteration of piperidine) + ox- + methyl + -ine entry 2

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The first known use of paroxetine was in 1977

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Cite this Entry

“Paroxetine.” Dictionary, Merriam-Webster, Accessed 18 Aug. 2022.

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More Definitions for paroxetine


par·​ox·​e·​tine | \ par-ˈäk-sə-ˌtēn How to pronounce paroxetine (audio) \

Medical Definition of paroxetine

: a drug that functions as an SSRI and is usually taken orally in the form of its hydrochloride C19H20FNO3·HCl or mesylate C19H20FNO3·CH4O3S to treat depression, anxiety, panic disorder, and obsessive-compulsive disorder and to relieve symptoms (such as hot flashes) of menopause

Note: Trademarks for paroxetine include Brisdelle, Paxil, and Pexeva.


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