par·​ox·​e·​tine | \ pa-ˈräk-sə-ˌtēn How to pronounce paroxetine (audio) \

Definition of paroxetine

: a drug C19H20FNO3 that enhances serotonin activity and is usually administered in the form of its hydrochloride to treat depression

Examples of paroxetine in a Sentence

Recent Examples on the Web

These days, about 5 percent of expectant mothers use antidepressants, most commonly, serotonin reuptake inhibitors, or SSRIs, such as citalopram (brand name Celexa), paroxetine (Paxil), or sertraline (Zoloft). Julia Belluz, Vox, "We’re beginning to learn how moms’ antidepressants can affect fetuses," 9 Apr. 2018 Studies have found that babies exposed to paroxetine (akaPaxil, Pexeva, and Brisdelle) are roughly twice as likely to be born with cardiovascular or other malformations than babies exposed to other antidepressants or no drugs at all. Elizabeth Narins, Cosmopolitan, "17 Things You Need to Know About Taking Antidepressants During Pregnancy," 11 Sep. 2017 Some 325 million prescriptions for antidepressants were filled last year in the United States, including 15 million for Paxil and paroxetine, according to IMS Health, a health care information company. Roni Caryn Rabin, New York Times, "Lawsuit Over a Suicide Points to a Risk of Antidepressants," 11 Sep. 2017 The doctors first treated her depression and panic symptoms with an antidepressant, paroxetine, and an anti-anxiety medication, clonazepam. Susan Scutti, CNN, "The woman who sweats blood from her palms and her face," 24 Oct. 2017 The results from the CDC study suggest that if a woman took paroxetine (aka Paxil) during her pregnancy, that risk could increase to 24 per 10,000 or 0.24 percent. Korin Miller, SELF, "What You Need to Know About Antidepressant Use During Pregnancy," 24 July 2017

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'paroxetine.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of paroxetine

1977, in the meaning defined above

History and Etymology for paroxetine

perhaps from International Scientific Vocabulary par- (alteration of piperidine) + ox- + methyl + -ine entry 2

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The first known use of paroxetine was in 1977

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par·​ox·​e·​tine | \ par-ˈäk-sə-ˌtēn How to pronounce paroxetine (audio) \

Medical Definition of paroxetine

: a drug that functions as an SSRI and is usually taken orally in the form of its hydrochloride C19H20FNO3·HCl or mesylate C19H20FNO3·CH4O3S to treat depression, anxiety, panic disorder, and obsessive-compulsive disorder and to relieve symptoms (such as hot flashes) of menopause

Note: Trademarks for paroxetine include Brisdelle, Paxil, and Pexeva.

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to complain fretfully

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