par·​ox·​e·​tine | \ pa-ˈräk-sə-ˌtēn How to pronounce paroxetine (audio) \

Definition of paroxetine

: a drug C19H20FNO3 that enhances serotonin activity and is usually administered in the form of its hydrochloride to treat depression

Examples of paroxetine in a Sentence

Recent Examples on the Web Risk for the coronavirus was reduced in those who had a pneumococcal polysaccharide or influenza vaccine, or were on melatonin, paroxetine, or carvedilol, according to Clinic research. Julie Washington, cleveland, 16 June 2020 Those who take melatonin as an over-the-counter sleep aid, the heart medication carvedilol or the anti-depressant paroxetine are less likely to test positive than patients who don’t take those medications, the study suggested. Julie Washington, cleveland, 16 June 2020 Of the 11 antidepressants analyzed, mirtazapine (Remeron) caused the greatest weight gain, followed by paroxetine (Paxil). Andrea Alfano, Scientific American, 1 July 2015 Some antidepressants, such as paroxetine, can be used to treat hot flashes at doses less than what is given for depression. Sandee Lamotte, CNN, 24 Sep. 2019 For women who don’t want to undergo estrogen therapy or who can’t for health reasons, Dr. Schaffir says that doctors will typically offer the anti-depressant paroxetine (aka Paxil), which can help relieve some menopausal symptoms. Korin Miller,, 17 Sep. 2019 These days, about 5 percent of expectant mothers use antidepressants, most commonly, serotonin reuptake inhibitors, or SSRIs, such as citalopram (brand name Celexa), paroxetine (Paxil), or sertraline (Zoloft). Julia Belluz, Vox, 9 Apr. 2018 Studies have found that babies exposed to paroxetine (akaPaxil, Pexeva, and Brisdelle) are roughly twice as likely to be born with cardiovascular or other malformations than babies exposed to other antidepressants or no drugs at all. Elizabeth Narins, Cosmopolitan, 11 Sep. 2017 Some 325 million prescriptions for antidepressants were filled last year in the United States, including 15 million for Paxil and paroxetine, according to IMS Health, a health care information company. Roni Caryn Rabin, New York Times, 11 Sep. 2017

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'paroxetine.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of paroxetine

1977, in the meaning defined above

History and Etymology for paroxetine

perhaps from International Scientific Vocabulary par- (alteration of piperidine) + ox- + methyl + -ine entry 2

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Time Traveler for paroxetine

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The first known use of paroxetine was in 1977

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Cite this Entry

“Paroxetine.” Dictionary, Merriam-Webster, Accessed 18 Jun. 2021.

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More Definitions for paroxetine


par·​ox·​e·​tine | \ par-ˈäk-sə-ˌtēn How to pronounce paroxetine (audio) \

Medical Definition of paroxetine

: a drug that functions as an SSRI and is usually taken orally in the form of its hydrochloride C19H20FNO3·HCl or mesylate C19H20FNO3·CH4O3S to treat depression, anxiety, panic disorder, and obsessive-compulsive disorder and to relieve symptoms (such as hot flashes) of menopause

Note: Trademarks for paroxetine include Brisdelle, Paxil, and Pexeva.


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