de·​sip·​ra·​mine | \ də-ˈzi-prə-ˌmēn How to pronounce desipramine (audio) \

Definition of desipramine

: a tricyclic antidepressant C18H22N2

Examples of desipramine in a Sentence

Recent Examples on the Web Those include medications that are known antidepressants such as bupropion and desipramine. Andrea K. Mcdaniels,, "Children aren't the only ones with ADHD; adults get it as well," 17 May 2018

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'desipramine.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

First Known Use of desipramine

1965, in the meaning defined above

History and Etymology for desipramine

desmethyl (from des- + methyl) + imipramine

Keep scrolling for more

Learn More about desipramine

Time Traveler for desipramine

Time Traveler

The first known use of desipramine was in 1965

See more words from the same year

Statistics for desipramine

Cite this Entry

“Desipramine.” Dictionary, Merriam-Webster, Accessed 5 Aug. 2020.

Keep scrolling for more

More Definitions for desipramine


de·​si·​pra·​mine | \ ˌdez-ə-ˈpram-ən How to pronounce desipramine (audio) , də-ˈzip-rə-ˌmēn How to pronounce desipramine (audio) \

Medical Definition of desipramine

: a tricyclic antidepressant administered in the form of its hydrochloride C18H22N2·HCl especially in the treatment of endogenous depressions (as bipolar disorder) — see norpramin, pertofrane

Comments on desipramine

What made you want to look up desipramine? Please tell us where you read or heard it (including the quote, if possible).


Test Your Vocabulary

July 2020 Words of the Day Quiz

  • papercraft sunset
  • Which is a synonym of mien?
Spell It

Can you spell these 10 commonly misspelled words?

Add Diction

Test Your Knowledge - and learn some interesting things along the way.

Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!