clo·​mip·​ra·​mine klō-ˈmi-prə-ˌmēn How to pronounce clomipramine (audio)
: a tricyclic antidepressant C19H23ClN2 used in the form of its hydrochloride to treat obsessive-compulsive disorder

Example Sentences

Recent Examples on the Web On Wednesday, the Food and Drug Administration announced the approval of clomipramine hydrochloride, a generic for the brand name drug Clomicalm, for dogs ages 6 months and up who have fears or underlying anxiety about being left alone. NBC News, 30 Oct. 2019 Yet the scarcity of clomipramine has little to do with Brexit. The Economist, 14 Sep. 2019 In August 2013, Walgreens drugstores, a Mylan customer, asked Sandoz to bid for supplying clomipramine. Ben Elginbloomberg, Los Angeles Times, 2 Aug. 2019 The companies, including those that make clomipramine, have denied the states’ allegations. Ben Elginbloomberg, Los Angeles Times, 2 Aug. 2019

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'clomipramine.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History


chlor- + imipramine

First Known Use

1975, in the meaning defined above

Time Traveler
The first known use of clomipramine was in 1975

Dictionary Entries Near clomipramine

Cite this Entry

“Clomipramine.” Dictionary, Merriam-Webster, Accessed 1 Apr. 2023.

Medical Definition


clo·​mip·​ra·​mine klō-ˈmip-rə-ˌmēn How to pronounce clomipramine (audio)
: a tricyclic antidepressant taken orally in the form of its hydrochloride C19H23ClN2·HCl to treat obsessive-compulsive disorder
Researchers agree that clomipramine dramatically reduces the repetitious behaviors of many people with obsessive compulsive disorder.Ron Cowen, Science News
Clomipramine is marketed under the trademark Anafranil.

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