imipenem

noun
im·​i·​pen·​em | \ ˌi-mə-ˈpe-nəm How to pronounce imipenem (audio) \

Definition of imipenem

: a semisynthetic carbapenem antibiotic C12H17N3O4S·H2O that is derived from a bacterium (Streptomyces cattleya) and is effective against gram-negative and gram-positive bacteria

First Known Use of imipenem

1983, in the meaning defined above

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The first known use of imipenem was in 1983

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“Imipenem.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/imipenem. Accessed 5 Dec. 2020.

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imipenem

noun
im·​i·​pen·​em | \ ˌim-ə-ˈpen-əm How to pronounce imipenem (audio) \

Medical Definition of imipenem

: a semisynthetic beta-lactam C12H17N3O4S·H2O that is derived from an antibiotic produced by a bacterium of the genus Streptomyces (S. cattleya) and is effective against gram-negative and gram-positive bacteria

Note: Because imipenem is hydrolyzed by a dipeptidase in the kidney, it is administered with cilastatin, an inhibitor of this enzyme.

Five days before admission, the patient was evaluated by an infectious-disease specialist and readmitted to the other hospital for intravenous administration of a three-day course of imipenem-cilastatin …— Stephen I. Pelton et al., The New England Journal of Medicine, 31 Aug. 2006

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