cilastatin

noun
ci·​la·​stat·​in | \ ˌsī-lə-ˈsta-tᵊn How to pronounce cilastatin (audio) \
variants: also cilastatin sodium

Medical Definition of cilastatin

: a drug C16H25N2O5SNa that is administered intravenously in combination with the antibiotic imipenem in order to increase its effectiveness by inhibiting enzymatic breakdown in the kidney Five days before admission, the patient was evaluated by an infectious-disease specialist and readmitted to the other hospital for intravenous administration of a three-day course of imipenem–cilastatin— Stephen I. Pelton et al., The New England Journal of Medicine, 31 Aug. 2006 Inclusion of cilastatin makes it possible to use imipenem against urinary tract infections.Chemical & Engineering News, 16 Dec. 1985

Learn More about cilastatin

Cite this Entry

“Cilastatin.” Merriam-Webster.com Medical Dictionary, Merriam-Webster, https://www.merriam-webster.com/medical/cilastatin. Accessed 6 Aug. 2020.

Comments on cilastatin

What made you want to look up cilastatin? Please tell us where you read or heard it (including the quote, if possible).

WORD OF THE DAY

Test Your Vocabulary

July 2020 Words of the Day Quiz

  • papercraft sunset
  • Which is a synonym of mien?
Spell It

Can you spell these 10 commonly misspelled words?

TAKE THE QUIZ
Syn City

Test Your Knowledge - and learn some interesting things along the way.

TAKE THE QUIZ
Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!