Medical Definition of ciguatoxin
: a potent heat-stable neurotoxin that is produced by a marine dinoflagellate (Gambierdiscus toxicus) and causes ciguatera poisoning in those who eat fish (as barracuda or amberjack) in which toxic levels of it have become concentrated
also
: any of several related neurotoxins causing ciguatera
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Merriam-Webster unabridged
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