carbapenem

noun
car·​ba·​pen·​em | \ ˌkär-bə-ˈpe-nəm How to pronounce carbapenem (audio) \

Definition of carbapenem

: any of a class of broad-spectrum antibiotics (such as imipenem) resistant to hydrolysis by beta-lactamase Another class of antibiotics, carbapenems, is used as an antibiotic of last resort for the most persistent infections.— Nicholas Bakalar

Examples of carbapenem in a Sentence

Recent Examples on the Web Some of these tested positive for New Delhi metallo-beta-lactamase-1 (NDM-1), an enzyme that makes bacteria resistant to a class of important antibiotics known as carbapenems. David Mateo Ricci, STAT, "Antibiotic resistance nearly killed me. That’s why I’m raising awareness of it," 31 Dec. 2019 Between 12 percent and 71 percent — depending on the species tested — were also resistant to carbapenems, a class of antibiotics once considered the last line of defense. New York Times, "The Ganges Brims With Dangerous Bacteria," 23 Dec. 2019 The urgent threats also included: Carbapenem-resistant acinetobacter; carbapenem-resistant enterobacteriaceae (CRE); drug-resistant Neisseria gonorrhoeae; and clostridioides difficile, or C. diff. Ryan W. Miller, USA TODAY, "Drug-resistant superbugs are killing thousands of Americans. Here's what you need to know about them," 16 Nov. 2019 Two groups of bacteria are also on the list: Acinetobacter, which is commonly found in soil and water and can cause infections in blood, the urinary tract, and the lungs, or in open wounds; and carbapenem-resistant Enterobacteriaceae, or CRE. Erika Edwards, NBC News, "Dangerous superbugs kill more people than previously thought," 13 Nov. 2019 Of those isolates, about 25 percent produced carbapenem-thwarting enzymes called carbapenemases. Beth Mole, Ars Technica, "“Nightmare” superbugs continue to lurk in US, but control efforts working," 4 Apr. 2018 The rise of antibiotic-resistant superbugs such as CRE (carbapenem-resistant Enterobacteriaceae), which can be fatal in up to half of patients, has made addressing these problems more urgent. Chad Terhune, latimes.com, "Hospitals and device makers still struggle to rid medical scopes of infectious bacteria," 23 Apr. 2018 The rise of antibiotic-resistant superbugs such as CRE (carbapenem-resistant Enterobacteriaceae), which can be fatal in up to half of patients, has made addressing these problems more urgent. Chad Terhune, Washington Post, "Study: Nearly Three-Quarters Of Commonly Used Medical Scopes Tainted By Bacteria," 23 Apr. 2018 Last year, public health labs around the country were asked to watch for and quickly respond to cases of advanced antibiotic resistance, especially to some last-resort antibiotics called carbapenems. Washington Post, "CDC: Drug-resistant ‘nightmare bacteria’ pose growing threat," 3 Apr. 2018

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'carbapenem.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of carbapenem

1979, in the meaning defined above

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The first known use of carbapenem was in 1979

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Cite this Entry

“Carbapenem.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/carbapenem. Accessed 13 Aug. 2020.

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More Definitions for carbapenem

carbapenem

noun
car·​ba·​pen·​em | \ ˌkär-bə-ˈpe-nəm How to pronounce carbapenem (audio) \

Medical Definition of carbapenem

: any of a class of broad-spectrum beta-lactam antibiotics (such as imipenem) having a five-membered ring system similar to the penicillins but containing a carbon atom instead of a sulfur atom It rendered the Klebsiella, which was already resistant to many antibiotics used in critical care medicine, insensitive to the only remaining group that worked reliably and safely—the carbapenems, the so-called drugs of last resort.— Maryn McKenna, Scientific American, April 2011

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