am·​ide | \ ˈa-ˌmīd How to pronounce amide (audio) , -məd \

Definition of amide

1 : an inorganic compound derived from ammonia by replacement of an atom of hydrogen with another element (such as a metal)
2 : any of a class of organic compounds derived from ammonia or an amine by replacement of hydrogen with an acyl group — compare amine, imide

Keep scrolling for more

Examples of amide in a Sentence

Recent Examples on the Web After briefly trying different polymer components — amides rather than esters — Carothers turned to other research topics. Virginia Postrel, Twin Cities, "Virginia Postrel: The iPhone of 1939 helped liberate Europe. And women.," 1 Nov. 2019

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'amide.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

First Known Use of amide

1836, in the meaning defined at sense 1

History and Etymology for amide

International Scientific Vocabulary, from New Latin ammonia

Keep scrolling for more

Learn More about amide

Time Traveler for amide

Time Traveler

The first known use of amide was in 1836

See more words from the same year

Statistics for amide

Cite this Entry

“Amide.” Dictionary, Merriam-Webster, Accessed 4 Dec. 2020.

Keep scrolling for more

More Definitions for amide


am·​ide | \ ˈam-ˌīd How to pronounce amide (audio) , -əd How to pronounce amide (audio) \

Medical Definition of amide

: an organic compound derived from ammonia or an amine by replacement of an atom of hydrogen with an acyl group — compare imide

Other Words from amide

amidic \ ə-​ˈmid-​ik, a-​ How to pronounce amidic (audio) \ adjective

More from Merriam-Webster on amide Encyclopedia article about amide

Comments on amide

What made you want to look up amide? Please tell us where you read or heard it (including the quote, if possible).


Test Your Vocabulary

Musical Words Quiz

  • gramophone
  • Which word describes a musical performance marked by the absence of instrumental accompaniment?
Spell It

Can you spell these 10 commonly misspelled words?

Syn City

Test Your Knowledge - and learn some interesting things along the way.

Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!