am·​ide ˈa-ˌmīd How to pronounce amide (audio)
: an inorganic compound derived from ammonia by replacement of an atom of hydrogen with another element (such as a metal)
: any of a class of organic compounds derived from ammonia or an amine by replacement of hydrogen with an acyl group compare amine, imide

Examples of amide in a Sentence

Recent Examples on the Web The team thinks this is the result of the chemical structure of the protein, in particular the way amide groups bond with water molecules. The Physics Arxiv Blog, Discover Magazine, 12 Oct. 2021 Surrounding this custom carbon plate is a thick layer of ultra-light, soft, and responsive PEBA (polyether block amide) foam. Cory Smith, Outside Online, 18 Oct. 2022 After briefly trying different polymer components — amides rather than esters — Carothers turned to other research topics. Virginia Postrel, Twin Cities, 1 Nov. 2019

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'amide.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History


International Scientific Vocabulary, from New Latin ammonia

First Known Use

1836, in the meaning defined at sense 1

Time Traveler
The first known use of amide was in 1836

Dictionary Entries Near amide

Cite this Entry

“Amide.” Dictionary, Merriam-Webster, Accessed 17 Jul. 2024.

Medical Definition


am·​ide ˈam-ˌīd How to pronounce amide (audio) -əd How to pronounce amide (audio)
: an organic compound derived from ammonia or an amine by replacement of an atom of hydrogen with an acyl group compare imide
amidic adjective

More from Merriam-Webster on amide

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