sul·​fon·​amide ˌsəl-ˈfä-nə-ˌmīd How to pronounce sulfonamide (audio)
: any of various amides (such as sulfanilamide) of a sulfonic acid
also : sulfa drug

Example Sentences

Recent Examples on the Web The researchers examined which children had been given prescriptions for penicillin, penicillin with B-lactamase inhibitor, cephalosporin, sulfonamide or macrolide within the first six months of life. Jacqueline Howard, CNN, 20 Dec. 2019 Any positive test results for sulfonamides could be the result of leftover antibiotics from that time or intentional misuse, Jonker said. Rebekah Tuchscherer, USA TODAY, 26 June 2019 Other antibiotics found to raise the risk of miscarriage include most macrolides, quinolones, tetracyclines, sulfonamides and metronidazole. Paul Sisson,, 2 May 2017

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'sulfonamide.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

Word History


sulfonic + amide

First Known Use

1881, in the meaning defined above

Time Traveler
The first known use of sulfonamide was in 1881

Dictionary Entries Near sulfonamide

Cite this Entry

“Sulfonamide.” Dictionary, Merriam-Webster, Accessed 27 Nov. 2022.

Medical Definition



variants or chiefly British sulphonamide
: any of various amides (as sulfanilamide) of a sulfonic acid
also : sulfa drug

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