hy·​al·​uron·​i·​dase | \ ˌhī(-ə)l-yu̇-ˈrä-nə-ˌdās How to pronounce hyaluronidase (audio) , -ˌdāz \

Definition of hyaluronidase

: a mucolytic enzyme that facilitates the spread of fluids through tissues by lowering the viscosity of hyaluronic acid

Examples of hyaluronidase in a Sentence

Recent Examples on the Web Always choose hyaluronic acid fillers Keep in mind that hyaluronic acid is the only type of filler that can be dissolved and reversed using hyaluronidase. Dr. Leslie Baumann, miamiherald, "Unhappy with the dermal fillers you got? Here's how to fix," 11 June 2018 Yes, pretty much — hyaluronidase can deflate your fillers like a balloon. Kathleen Hou, The Cut, "How Do You Remove Lip Fillers?," 9 July 2018 Because HA is not permanent, your dermatologist can inject an eraser enzyme called hyaluronidase. Brooke Shunatona, Cosmopolitan, "18 Things You Should Know Before Getting Lip Injections," 27 May 2015 Fillers made with hyaluronic acid — such as Juvederm and Restylane — can be injected with hyaluronidase to dissolve the acid. Lisa Gutierrez, kansascity.com, "‘I’m as natural as I can be’: Courteney Cox has wrinkle fillers removed from her face," 23 June 2017

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'hyaluronidase.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of hyaluronidase

1940, in the meaning defined above

History and Etymology for hyaluronidase

International Scientific Vocabulary, from hyaluronic (acid) + -idase (as in glucosidase)

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Time Traveler for hyaluronidase

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The first known use of hyaluronidase was in 1940

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Cite this Entry

“Hyaluronidase.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/hyaluronidase. Accessed 27 Jan. 2021.

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More Definitions for hyaluronidase


hy·​al·​uron·​i·​dase | \ -ˈrän-ə-ˌdās, -ˌdāz How to pronounce hyaluronidase (audio) \

Medical Definition of hyaluronidase

: a mucolytic enzyme that splits and lowers the viscosity of hyaluronic acid facilitating the spreading of fluid through tissues either advantageously (as in the absorption of drugs) or disadvantageously (as in the dissemination of infection), that occurs in many normal tissues, in malignant growths, in invasive bacteria, and in certain venoms, and that is used especially to aid in the dispersion of fluids (as local anesthetics) injected subcutaneously for therapeutic purposes

called also spreading factor

More from Merriam-Webster on hyaluronidase

Britannica.com: Encyclopedia article about hyaluronidase

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