Definition of exonuclease
: an enzyme that breaks down a nucleic acid by removing nucleotides one by one from the end of a chain — compare endonuclease
Recent Examples of exonuclease from the Web
Double stranded DNA fragments with overlapping sequence stretches are inserted into a reaction, and exonuclease enzymes chew back one end of each piece, exposing complementary sequences that link up, joining the two fragments together.
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First Known Use of exonuclease
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