cholinesterase

noun
cho·​lin·​es·​ter·​ase | \ ˌkō-lə-ˈne-stə-ˌrās How to pronounce cholinesterase (audio) , -ˌrāz \

Definition of cholinesterase

1 : an enzyme that occurs chiefly at neuromuscular junctions and promotes the hydrolysis of acetylcholine at postsynaptic receptors : acetylcholinesterase

Examples of cholinesterase in a Sentence

Recent Examples on the Web Donepezil and others like it, such galantamine and rivastigmine, belong to a class of medications called cholinesterase inhibitors, typically prescribed for mild to moderate Alzheimer's disease. Jacqueline Howard, CNN, 9 June 2021 Carbamates and organophosphates, both pesticides, use cholinesterase inhibitors to neutralize the nervous system of insects. Miriam Berger, Washington Post, 26 Aug. 2020 The nerve agent is a cholinesterase inhibitor, part of the class of substances that doctors at Charite said last week had shown up in Navalny's system. Arkansas Online, 2 Sep. 2020 The nerve agent is a cholinesterase inhibitor, part of the class of substances that doctors at the Charite initially identified in Navalny. Geir Moulson, Anchorage Daily News, 2 Sep. 2020 Still, Loeb notes that cholinesterase inhibitors, which are often used for people with Alzheimer's, can help improve cognition and alertness in patients with Lewy body dementia. Jayme Deerwester, USA TODAY, 2 Sep. 2020 German doctors have confirmed Navalny had symptoms of poisoning, likely by a cholinesterase inhibitor, which includes highly toxic chemical nerve agents and pesticides. Robyn Dixon, Washington Post, 31 Aug. 2020 Doctors in Berlin said he was exposed to a cholinesterase inhibitor, a chemical group that includes some nerve agents, though the exact compound hasn’t yet been identified. Iain Rogers, Bloomberg.com, 29 Aug. 2020 Found in some drugs, pesticides and chemical nerve agents, cholinesterase inhibitors block the breakdown of a key chemical in the body, acetycholine, that transmits signals between nerve cells. Fox News, 28 Aug. 2020 See More

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'cholinesterase.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

First Known Use of cholinesterase

1932, in the meaning defined at sense 1

Learn More About cholinesterase

Time Traveler for cholinesterase

Time Traveler

The first known use of cholinesterase was in 1932

See more words from the same year

Dictionary Entries Near cholinesterase

cholinergic

cholinesterase

cholla

See More Nearby Entries 

Statistics for cholinesterase

Cite this Entry

“Cholinesterase.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/cholinesterase. Accessed 10 Aug. 2022.

Style: MLA
MLACheck Mark Icon ChicagoCheck Mark Icon APACheck Mark Icon Merriam-WebsterCheck Mark Icon

More Definitions for cholinesterase

cholinesterase

noun
cho·​lin·​es·​ter·​ase | \ ˌkō-lə-ˈnes-tə-ˌrās, -ˌrāz How to pronounce cholinesterase (audio) \

Medical Definition of cholinesterase

1 : an enzyme that occurs chiefly at neuromuscular junctions and promotes the hydrolysis of acetylcholine at postsynaptic receptors : acetylcholinesterase The acetylcholine released by cholinergic fibers is rapidly decomposed by the action of cholinesterase.— John W. Hole, Human Anatomy & Physiology As a cholinesterase inhibitor, it increases parasympathetic nervous system activity.— T. A. Farley et al., The Journal of the American Medical Association

More from Merriam-Webster on cholinesterase

Britannica.com: Encyclopedia article about cholinesterase

WORD OF THE DAY

Test Your Vocabulary

Words Named After People

  • name tags
  • Namesake of the leotard, Jules Léotard had what profession?
How Strong Is Your Vocabulary?

Test your vocabulary with our 10-question quiz!

TAKE THE QUIZ
Universal Daily Crossword

A daily challenge for crossword fanatics.

TAKE THE QUIZ
Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!