neur·​amin·​i·​dase | \ ˌnu̇r-ə-ˈmi-nə-ˌdās How to pronounce neuraminidase (audio) , ˌnyu̇r-, -ˌdāz \

Definition of neuraminidase

: a hydrolytic enzyme that occurs on the surface of the pneumococcus, influenza-causing viruses, and some paramyxoviruses as an antigen and that splits mucoproteins by breaking a glucoside link

Examples of neuraminidase in a Sentence

Recent Examples on the Web As for treatment of avian influenza viruses, the CDC recommends what's known as a neuraminidase inhibitor—like oseltamivir, peramivir, and zanamivir—a type of antiviral drug that can block reproduction of the virus. Maggie O'neill,, 1 June 2021 Viral code The Hs and Ns refer to hemagglutinin (Ha or H) and neuraminidase (Na or N), respectively, which are both viral molecules that hang on the outside of viral particles. Beth Mole, Ars Technica, 10 Dec. 2019 The flu virus normally infects cells in the lungs by binding through its haemagglutinin and neuraminidase proteins to sialic acid on the surface of lung cells. Neil Savage, Scientific American, 18 Sep. 2019 Virologists classify these viruses into subtypes based on two proteins on their surface, haemagglutinin (H) and neuraminidase (N). Cassandra Willyard, Scientific American, 18 Sep. 2019 They are classified by numbers based on the subtype of haemagglutinin (H) protein and a second viral protein known as neuraminidase (N), with even greater strain variation observed among those subtypes. Michael Eisenstein, Scientific American, 18 Sep. 2019 These drugs inhibit neuraminidase, an enzyme that allows viruses to escape from one cell and spread to others. Neil Savage, Scientific American, 18 Sep. 2019 Another neuraminidase inhibitor, peramivir, which is administered intravenously, has been approved for use in the United States, Japan and South Korea. Neil Savage, Scientific American, 18 Sep. 2019 There are only two other classes of flu drugs, neuraminidase inhibitors (drugs like Tamiflu, Relenza, Rapivab) and the adamantane drugs (amantadine and rimantadine). Helen Branswell, STAT, 27 June 2018

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'neuraminidase.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of neuraminidase

1957, in the meaning defined above

History and Etymology for neuraminidase

neuraminic acid, an amino acid + -ide + -ase

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The first known use of neuraminidase was in 1957

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neural tube



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Last Updated

5 Jun 2021

Cite this Entry

“Neuraminidase.” Dictionary, Merriam-Webster, Accessed 29 Jul. 2021.

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More Definitions for neuraminidase


neur·​amin·​i·​dase | \ ˌn(y)u̇r-ə-ˈmin-ə-ˌdās, -ˌdāz How to pronounce neuraminidase (audio) \

Medical Definition of neuraminidase

: a hydrolytic enzyme that occurs on the surface of the pneumococcus, the orthomyxoviruses, and some paramyxoviruses and that cleaves terminal acetylated neuraminic acids from sugar residues (as in glycoproteins and mucoproteins)

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