neur·​amin·​i·​dase | \ ˌnu̇r-ə-ˈmi-nə-ˌdās How to pronounce neuraminidase (audio) , ˌnyu̇r-, -ˌdāz \

Definition of neuraminidase

: a hydrolytic enzyme that occurs on the surface of the pneumococcus, influenza-causing viruses, and some paramyxoviruses as an antigen and that splits mucoproteins by breaking a glucoside link

Examples of neuraminidase in a Sentence

Recent Examples on the Web Two viruses may have the same broad hemagglutinin and neuraminidase subtypes, but have subtle differences throughout their genome. William A. Haseltine, Forbes, 12 Aug. 2022 The subtyping of the neuraminidase — the N in the virus’ name — is still underway, but the presumption is that the birds and the man were infected with H5N1 viruses. Helen Branswell, STAT, 4 May 2022 The subtypes for influenza A are broken down based on two proteins on the surface of the virus, the CDC explains: hemagglutinin (H) and neuraminidase (N). Korin Miller,, 18 Nov. 2021 The surface of all influenza strains is studded with proteins, the most important of which, for Influenza A and B, are hemagglutinin (HA) and neuraminidase (NA). New York Times, 8 Dec. 2021 There are 18 different hemagglutinin subtypes and 11 different neuraminidase subtypes (H1 through H18 and N1 through N11). Korin Miller,, 18 Nov. 2021 As for treatment of avian influenza viruses, the CDC recommends what's known as a neuraminidase inhibitor—like oseltamivir, peramivir, and zanamivir—a type of antiviral drug that can block reproduction of the virus. Maggie O'neill,, 1 June 2021 Viral code The Hs and Ns refer to hemagglutinin (Ha or H) and neuraminidase (Na or N), respectively, which are both viral molecules that hang on the outside of viral particles. Beth Mole, Ars Technica, 10 Dec. 2019 The flu virus normally infects cells in the lungs by binding through its haemagglutinin and neuraminidase proteins to sialic acid on the surface of lung cells. Neil Savage, Scientific American, 18 Sep. 2019 See More

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'neuraminidase.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

First Known Use of neuraminidase

1957, in the meaning defined above

History and Etymology for neuraminidase

neuraminic acid, an amino acid + -ide + -ase

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The first known use of neuraminidase was in 1957

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Dictionary Entries Near neuraminidase

neural tube



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Last Updated

16 Aug 2022

Cite this Entry

“Neuraminidase.” Dictionary, Merriam-Webster, Accessed 24 Sep. 2022.

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More Definitions for neuraminidase


neur·​amin·​i·​dase | \ ˌn(y)u̇r-ə-ˈmin-ə-ˌdās, -ˌdāz How to pronounce neuraminidase (audio) \

Medical Definition of neuraminidase

: a hydrolytic enzyme that occurs on the surface of the pneumococcus, the orthomyxoviruses, and some paramyxoviruses and that cleaves terminal acetylated neuraminic acids from sugar residues (as in glycoproteins and mucoproteins)

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