neuraminidase

noun

neur·​amin·​i·​dase ˌnu̇r-ə-ˈmi-nə-ˌdās How to pronounce neuraminidase (audio)
ˌnyu̇r-,
-ˌdāz
: a hydrolytic enzyme that occurs on the surface of the pneumococcus, influenza-causing viruses, and some paramyxoviruses as an antigen and that splits mucoproteins by breaking a glucoside link

Examples of neuraminidase in a Sentence

Recent Examples on the Web Flu vaccines often generate immune responses to fast-evolving bits of proteins on the outside of flu virus particles, hemagglutinin (Ha or H) and neuraminidase (Na or N). Ashley Belanger, Ars Technica, 16 May 2023 Several also add neuraminidase, a protein on the surface of the flu virus that controls how viral copies break free from cells. Maryn McKenna, WIRED, 10 Nov. 2023 With 18 hemagglutinin and 11 neuraminidase proteins known, the permutations and combinations are many, leading to a high number of variants. Larry Brilliant, Foreign Affairs, 20 Dec. 2022 But resistant strains have a mutation in their neuraminidase gene, which changes a single amino acid in the protein’s sequence. Ed Yong, Discover Magazine, 3 June 2010 The World Health Organization, which adopted the classification system in 1979, further divided influenza A based on its surface glycoproteins, hemagglutinin (H) and neuraminidase (N). Brenda Poppy, Discover Magazine, 14 Oct. 2015 Drugs like oseltamivir inhibit the spread of viral infection in a host by blocking the neuraminidase. Gemma Tarlach, Discover Magazine, 10 Dec. 2013 Different types of neuraminidase---the N's---govern how the virus spreads through a host. Gemma Tarlach, Discover Magazine, 10 Dec. 2013 Two viruses may have the same broad hemagglutinin and neuraminidase subtypes, but have subtle differences throughout their genome. William A. Haseltine, Forbes, 12 Aug. 2022 See More

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'neuraminidase.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History

Etymology

neuraminic acid, an amino acid + -ide + -ase

First Known Use

1957, in the meaning defined above

Time Traveler
The first known use of neuraminidase was in 1957

Dictionary Entries Near neuraminidase

Cite this Entry

“Neuraminidase.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/neuraminidase. Accessed 22 Feb. 2024.

Medical Definition

neuraminidase

noun
neur·​amin·​i·​dase ˌn(y)u̇r-ə-ˈmin-ə-ˌdās, -ˌdāz How to pronounce neuraminidase (audio)
: a hydrolytic enzyme that occurs on the surface of the pneumococcus, the orthomyxoviruses, and some paramyxoviruses and that cleaves terminal acetylated neuraminic acids from sugar residues (as in glycoproteins and mucoproteins)

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