Definition of topoisomerase
: any of a class of enzymes that reduce supercoiling in DNA by breaking and rejoining one or both strands of the DNA molecule
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Origin and Etymology of topoisomerase
top- + isomerase
First Known Use: 1980
Medical Dictionary
topoisomerase
play
noun
topo·isom·er·ase
\ˌtō-pō-ī-ˈsäm-ə-ˌrās, -ˌrāz\
Medical Definition of topoisomerase
: any of a class of enzymes that reduce supercoiling in DNA by breaking and rejoining one or both strands of the DNA molecule
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