acetylcholinesterase

noun ace·tyl·cho·lin·es·ter·ase \ -ˌkō-lə-ˈnes-tə-ˌrās , -ˌrāz \
Updated on: 13 Apr 2018

Definition of acetylcholinesterase

: an enzyme that occurs chiefly in cholinergic nerve endings and promotes the hydrolysis of acetylcholine : cholinesterase 1
Note: Acetylcholinesterase is also found in red blood cells, where its function is unknown.

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Origin and Etymology of acetylcholinesterase


Medical Dictionary

acetylcholinesterase

noun ace·tyl·cho·lin·es·ter·ase \ -ˌkō-lə-ˈnes-tə-ˌrās, -ˌrāz \

medical Definition of acetylcholinesterase

: an enzyme that occurs chiefly in cholinergic nerve endings and promotes the hydrolysis of acetylcholine : cholinesterase 1
  • The therapeutic rationale is that inhibition of acetylcholinesterase enhances sympathetic ganglionic neurotransmission and that the effect is maximal when the patient is upright, since sympathetic-nerve traffic is greatest in this position.
  • —Roy FreemanThe New England Journal of Medicine7 Feb. 2008
  • Tacrine is a potent, centrally active, reversible acetylcholinesterase inhibitor that prevents the degradation of endogenously released acetylcholine.
  • —Margaret J. Knapp et al.The Journal of the American Medical Association6 Apr. 1994
Note: Acetylcholinesterase is also found in red blood cells where its function there is unknown.


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