First Known Use of acetylcholinesterase
medical Definition of acetylcholinesterase
- The therapeutic rationale is that inhibition of acetylcholinesterase enhances sympathetic ganglionic neurotransmission and that the effect is maximal when the patient is upright, since sympathetic-nerve traffic is greatest in this position.
- —Roy Freeman, The New England Journal of Medicine, 7 Feb. 2008
- Tacrine is a potent, centrally active, reversible acetylcholinesterase inhibitor that prevents the degradation of endogenously released acetylcholine.
- —Margaret J. Knapp et al., The Journal of the American Medical Association, 6 Apr. 1994
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