hyaluronic acid

noun

hy·​al·​uron·​ic acid ˌhī(-ə)l-yu̇-ˈrä-nik 

: a viscous glycosaminoglycan chiefly of the matrix of tissues that occurs especially in the vitreous humor, umbilical cord, synovial fluid, and loose connective tissue and serves especially as a structural element and lubricant

Examples of hyaluronic acid in a Sentence

Recent Examples on the Web

It’s got caffeine, peptides, hyaluronic acid, and niacinamide for instant depuffing, plumping, moisturizing, and brightening — a powerhouse blend that immediately won our tester over. —Esme Benjamin, People.com, 6 Aug. 2025

Kosas is a mainstay in her beauty bag; the cruelty-free formula features peptides, caffeine, and hyaluronic acid to actively reduce dull skin and puffiness. —Conçetta Ciarlo, Vogue, 5 Aug. 2025

The Water Drench Ice-Facial Cooling Mist is infused with hydrating hyaluronic acid, brightening caffeine, and a trio of antioxidant-rich green, red, and white tea to protect skin from damage caused by free radicals. —Lily Wohlner, Allure, 4 Aug. 2025

The fine mist format offers easy, even coverage — especially on hard-to-reach spots like the back of the legs — while hyaluronic acid and vitamins C and E deliver hydration and antioxidant protection. —Claire Sullivan, Footwear News, 1 Aug. 2025

Word History

Etymology

International Scientific Vocabulary

First Known Use

1934, in the meaning defined above

Rhymes for hyaluronic acid

• antacid
• placid

Medical Definition

hyaluronic acid

noun

hy·​al·​uron·​ic acid ˌhīl-yu̇-ˌrän-ik-  ˌhī-əl-yu̇- 

: a viscous glycosaminoglycan that occurs especially in the vitreous body, the umbilical cord, and synovial fluid and as a cementing substance in the subcutaneous tissue