hyaluronic acid

noun

hy·​al·​uron·​ic acid ˌhī(-ə)l-yu̇-ˈrä-nik 

: a viscous glycosaminoglycan chiefly of the matrix of tissues that occurs especially in the vitreous humor, umbilical cord, synovial fluid, and loose connective tissue and serves especially as a structural element and lubricant

Examples of hyaluronic acid in a Sentence

Recent Examples on the Web

My go-to is the Summer Fridays Jet Lag Mask, a hydrating moisturizer and mask with hyaluronic acid that triples as a daily moisturizer, overnight face mask, and a rich, non-greasy hand cream. —Annita Katee, Travel + Leisure, 16 Dec. 2025

The formula is enriched with a host of hydrating agents from hyaluronic acid to rosehip oil, which keeps lips soft, smooth, and chap-free. —Kiana Murden, Vogue, 15 Dec. 2025

The Dahlia Rouge Hand Cream is intensely moisturizing yet fast-absorbing, packed with nourishing argan oil, plumping hyaluronic acid, smoothing squalane, and a rich blend of cocoa and shea butters that leave skin incredibly soft. —Lily Wohlner, Allure, 12 Dec. 2025

Our top pick overall was the Medicube Triple Collagen Cream because its affordable and its potent formula blends collagen with hyaluronic acid and shea butter to deeply hydrate. —Deanna Pai, Glamour, 11 Dec. 2025

Word History

Etymology

International Scientific Vocabulary

First Known Use

1934, in the meaning defined above

Rhymes for hyaluronic acid

• antacid
• placid

Medical Definition

hyaluronic acid

noun

hy·​al·​uron·​ic acid ˌhīl-yu̇-ˌrän-ik-  ˌhī-əl-yu̇- 

: a viscous glycosaminoglycan that occurs especially in the vitreous body, the umbilical cord, and synovial fluid and as a cementing substance in the subcutaneous tissue