hyaluronic acid

noun

hy·​al·​uron·​ic acid ˌhī(-ə)l-yu̇-ˈrä-nik 

: a viscous glycosaminoglycan chiefly of the matrix of tissues that occurs especially in the vitreous humor, umbilical cord, synovial fluid, and loose connective tissue and serves especially as a structural element and lubricant

Examples of hyaluronic acid in a Sentence

Recent Examples on the Web

The Triple Hyaluronic Acid and Lipopeptide Serum combines plumping hyaluronic acid with soothing ceramides and age-defying peptides for a hydrating, lightweight formula that reverses fine lines over time and creates the perfect, smooth base. —Kaitlin Clapinski, InStyle, 5 Mar. 2026

Simultaneously, a conditioning complex of peptides, ceramides, encapsulated hyaluronic acid, and botanical ingredients works to smooth, cushion, and replenish moisture where it’s most needed. —Kiana Murden, Vogue, 2 Mar. 2026

Meanwhile, 2% hyaluronic acid fills in for any lost hydration, so you’re left with a brighter, glowing complexion. —Annie Blackman, Allure, 28 Feb. 2026

The Ordinary Matrixyl + Hyaluronic Acid Serum The formula’s hydrating hyaluronic acid plumps the skin with every use, which reduces the appearance of fine lines while leaving a smooth, radiant finish. —Caley Sturgill, Southern Living, 27 Feb. 2026

Word History

Etymology

International Scientific Vocabulary

First Known Use

1934, in the meaning defined above

Rhymes for hyaluronic acid

• antacid
• placid

Medical Definition

hyaluronic acid

noun

hy·​al·​uron·​ic acid ˌhīl-yu̇-ˌrän-ik-  ˌhī-əl-yu̇- 

: a viscous glycosaminoglycan that occurs especially in the vitreous body, the umbilical cord, and synovial fluid and as a cementing substance in the subcutaneous tissue