creatine kinase

noun

: any of three isoenzymes found especially in vertebrate skeletal and myocardial muscle that catalyze the transfer of a high-energy phosphate group from phosphocreatine to ADP with the formation of ATP and creatine

Example Sentences

Recent Examples on the Web

Sanders checked muscle enzyme levels and found unusually high concentrations of the enzyme creatine kinase, an indicator of muscle injury. —Shilpa Ravella, Discover Magazine, 10 Mar. 2017

Instead, the biggest difference was in the blood levels of creatine kinase and lactate dehydrogenase, both markers of muscle damage, which were significantly elevated immediately after the race and 24 hours later in the crampers. —Alex Hutchinson, Outside Online, 1 Sep. 2020

For example, day-after creatine kinase averaged 2,439 international units per liter. —Alex Hutchinson, Outside Online, 1 Sep. 2020

Ue ordered additional tests to track the patient’s creatine kinase. —New York Times, 14 July 2021

The primary diagnostic tool for rhabdomyolysis is a blood test for creatine kinase. —Washington Post, 12 Feb. 2021

For athletes, the idea is that the increased blood flow also increases the clearance of blood lactate and creatine kinase, both of which get released from muscles and into the bloodstream after vigorous exercise and is a signal of muscle damage. —Claire Maldarelli, Popular Science, 17 Jan. 2019

The key for patients who have muscle symptoms while on statins lies in a blood test known as creatine kinase, or CK, an enzyme found in muscles. —Richard Klasco, New York Times, 1 June 2018

The key for patients who have muscle symptoms while on statins lies in a blood test known as creatine kinase, or CK, an enzyme found in muscles. —Richard Klasco, New York Times, 1 June 2018

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Word History

First Known Use

1964, in the meaning defined above

Medical Definition

creatine kinase

noun

: any of three isoenzymes found especially in vertebrate skeletal and myocardial muscle and the brain that catalyze the transfer of a high-energy phosphate group from phosphocreatine to ADP with the formation of ATP and creatine and typically occur in elevated levels in the blood following injury to brain or muscle tissue