cre·​a·​tine ˈkrē-ə-ˌtēn How to pronounce creatine (audio)
: a white crystalline nitrogenous substance C4H9N3O2 found especially in the muscles of vertebrates either free or as phosphocreatine
also : a synthetic usually hydrated form of creatine taken especially as a dietary supplement

Examples of creatine in a Sentence

Recent Examples on the Web Research has shown that creatine supplementation can significantly improve strength, power, and exercise performance, especially in activities involving intense muscle contractions. Amber Smith, Discover Magazine, 6 Oct. 2023 Discover how to buy an effective creatine supplement here. David McGlynn, Men's Health, 7 June 2023 If building strong muscles, increasing explosiveness, and recovering better than ever sound appealing, then creatine should be on your radar. Andi Breitowich, Women's Health, 6 Sep. 2023 Or someone in your life has decided to start taking creatine supplements. Olivia Munson, USA TODAY, 14 Aug. 2023 Worth noting, more research is needed on how creatine supplementation particularly affects women, says Michael Hamlin, CSCS, founder of Everflex Fitness. Andi Breitowich, Women's Health, 6 Sep. 2023 Despite being able to make creatine naturally in your body and obtain it from dietary sources, creatine is widely discussed as a popular supplement. Perri O. Blumberg, Men's Health, 28 Aug. 2023 Combining creatine with 50 grams of protein and 50 grams of carbohydrates is more effective than taking creatine solo. Addison Aloian, Women's Health, 5 Sep. 2023 Among the most powerful: That creatine causes hair loss. David McGlynn, Men's Health, 7 June 2023 See More

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'creatine.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History


French créatine, from Greek kreat-, kreas flesh — more at raw

First Known Use

1840, in the meaning defined above

Time Traveler
The first known use of creatine was in 1840

Dictionary Entries Near creatine

Cite this Entry

“Creatine.” Dictionary, Merriam-Webster, Accessed 6 Dec. 2023.

Medical Definition


: a white crystalline nitrogenous substance C4H9N3O2 found especially in vertebrate muscle either free or as phosphocreatine

More from Merriam-Webster on creatine

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