creatine

noun

cre·​a·​tine ˈkrē-ə-ˌtēn 

-tᵊn

: a white crystalline nitrogenous substance C₄H₉N₃O₂ found especially in the muscles of vertebrates either free or as phosphocreatine

also : a synthetic usually hydrated form of creatine taken especially as a dietary supplement

Examples of creatine in a Sentence

Recent Examples on the Web

Creatine For most people, combining creatine and protein powder is perfectly safe and may even enhance nutrient uptake and performance benefits. —Currie Engel, Health, 13 Nov. 2025

The benefits of creatine are many, and below, top dieticians and nutritionists weigh in on the best creatine supplements, what to look for, and how to incorporate them into your routine. —Brianna Peters, Vogue, 9 Nov. 2025

Including both creatine and protein in your diet may give you even better results for your overall workout performance and recovery. —Jessica Swirble, Verywell Health, 14 Oct. 2025

Combining creatine with nutrients like vitamin B12 may also help promote better overall energy and heart function. —Angelica Stabile, FOXNews.com, 11 Oct. 2025

Word History

Etymology

French créatine, from Greek kreat-, kreas flesh — more at raw

First Known Use

1840, in the meaning defined above

Phrases Containing creatine

• creatine kinase
• creatine phosphate

Rhymes for creatine

• aten
• clayton
• satan
• statin
• straighten

Medical Definition

creatine

noun

cre·​atine ˈkrē-ə-ˌtēn, -ət-ᵊn 

: a white crystalline nitrogenous substance C₄H₉N₃O₂ found especially in vertebrate muscle either free or as phosphocreatine