creatine

noun

cre·​a·​tine ˈkrē-ə-ˌtēn 

-tᵊn

: a white crystalline nitrogenous substance C₄H₉N₃O₂ found especially in the muscles of vertebrates either free or as phosphocreatine

also : a synthetic usually hydrated form of creatine taken especially as a dietary supplement

Examples of creatine in a Sentence

Recent Examples on the Web

Taking creatine with foods that contain carbohydrates, a main source of energy in the body, or mixing it with carbs and protein may help your body store more creatine. —Merve Ceylan, Health, 7 July 2025

Four of six popular creatine gummy products sold on Amazon contained almost no creatine or none at all when samples were tested by an independent lab. —Kate Knibbs, Wired News, 18 June 2025

Combining creatine with resistance training, such as push-ups, sit-ups, and crunches, can provide more health benefits.8 Vegetarians may also benefit from taking creatine. —Health, 17 June 2025

In a small pilot study, his team found that taking 20 grams of creatine daily for eight weeks was safe and boosted the creatine in participants’ brains. —Staff Author Published, Verywell Health, 11 June 2025

Word History

Etymology

French créatine, from Greek kreat-, kreas flesh — more at raw

First Known Use

1840, in the meaning defined above

Phrases Containing creatine

• creatine kinase
• creatine phosphate

Rhymes for creatine

• aten
• clayton
• satan
• statin
• straighten

Medical Definition

creatine

noun

cre·​atine ˈkrē-ə-ˌtēn, -ət-ᵊn 

: a white crystalline nitrogenous substance C₄H₉N₃O₂ found especially in vertebrate muscle either free or as phosphocreatine