creatine

noun

cre·​a·​tine ˈkrē-ə-ˌtēn 

-tᵊn

: a white crystalline nitrogenous substance C₄H₉N₃O₂ found especially in the muscles of vertebrates either free or as phosphocreatine

also : a synthetic usually hydrated form of creatine taken especially as a dietary supplement

Examples of creatine in a Sentence

Recent Examples on the Web

In another study, researchers found that when participants took 4 grams of creatine daily for about six months, creatine helped reduce fatigue in people with long COVID.30 Creatine supplementation is likely safe for short-term use. —Emmanuella Ogbonna, Health, 7 Aug. 2025

People who take creatine supplements typically experience more significant muscle growth than those who do not. —Kelly Burch Published, Verywell Health, 30 July 2025

Naturally found in muscle and brain tissue, creatine helps women maintain strength, muscle mass, and cognitive clarity as hormone levels shift. —Kate Donnelly, Forbes.com, 28 July 2025

As a result, creatine supplements have become a popular way to increase the creatine in the muscles. —Joshua Rapp Learn, Discover Magazine, 11 July 2025

Word History

Etymology

French créatine, from Greek kreat-, kreas flesh — more at raw

First Known Use

1840, in the meaning defined above

Phrases Containing creatine

• creatine kinase
• creatine phosphate

Rhymes for creatine

• aten
• clayton
• satan
• statin
• straighten

Medical Definition

creatine

noun

cre·​atine ˈkrē-ə-ˌtēn, -ət-ᵊn 

: a white crystalline nitrogenous substance C₄H₉N₃O₂ found especially in vertebrate muscle either free or as phosphocreatine