an·​ti·​hor·​mone | \ ˌan-tē-ˈhȯr-ˌmōn How to pronounce antihormone (audio) , ˌan-tī- \

Definition of antihormone

: a substance (such as tamoxifen) that blocks the action or inhibits the production of a hormone

First Known Use of antihormone

1908, in the meaning defined above

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The first known use of antihormone was in 1908

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Cite this Entry

“Antihormone.” Dictionary, Merriam-Webster, Accessed 25 Nov. 2020.

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an·​ti·​hor·​mone | \ -ˈhȯr-ˌmōn \

Medical Definition of antihormone

 (Entry 1 of 2)

1 : a substance (as tamoxifen) that blocks the action or inhibits the production of a hormone … a group of naturally occurring plant chemicals that weakly mimic the effects of estrogen hormones in some parts of the body while acting like antihormones in others.— Christine Gorman, Time
2 dated : a fraction of blood globulin that is capable of rendering ineffective a protein-containing heterologous hormone when the latter is administered over a period of time and that is now generally considered to be a true antibody formed in response to the presence of foreign protein Although subsequent work disproved the idea that antihormones played any physiological role in the control of endocrine organs, these experiments excited wide interest at the time and raised the question of species-specificity of protein hormones in therapeutic procedures.— R. L. Noble, The Canadian Medical Association Journal


variants: also anti-hormone

Medical Definition of antihormone (Entry 2 of 2)

: of, relating to, or using antihormones : antihormonal antihormone treatment

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