testosterone

noun

tes·​tos·​ter·​one te-ˈstä-stə-ˌrōn 

1

: a hormone that is a hydroxy steroid ketone C₁₉H₂₈O₂ produced especially by the testes or made synthetically and that is responsible for inducing and maintaining male secondary sex characters

2

: qualities (such as brawn and aggressiveness) usually associated with males : manliness

Examples of testosterone in a Sentence

Recent Examples on the Web

Christine is a recent appointee who, until recently, was a urologist specializing in testosterone and male fertility issues. —Amy Maxmen, Miami Herald, 11 Feb. 2026

Cholesterol is a waxy, fat-like substance the body uses to build cells and make hormones such as testosterone and estrogen. —Akshay Syal, NBC news, 8 Feb. 2026

Last year, the company launched its low-testosterone treatment program and bought a peptide-manufacturing facility. —Yasmin Tayag, The Atlantic, 8 Feb. 2026

Boxer Imane Khelif admitted to having the SRY gene, located on the Y chromosome, which is found in biological males, and undergoing hormone treatments to lower testosterone levels ahead of the 2024 Olympics in an interview with the French sports publication L'Equipe. —Jackson Thompson, FOXNews.com, 6 Feb. 2026

Word History

Etymology

borrowed from German Testosteron, from Latin testēs testes + German -o- -o- + -steron -sterone

Note: The name was introduced by the Hungarian pharmacologists Karoly Gyula David (1905-45) and János Freud (1901-48), the Dutch endocrinologist Elisabeth Dingemanse (1886-1952), and the German-born Dutch physician and pharmacologist Ernst Laqueur (1880-1947) (all affiliated with the Pharmaco-Therapeutic Laboratory of the University of Amsterdam) in "Über krystallinisches männliches Hormon aus Hoden (Testosteron), wirksamer als aus Harn oder aus Cholesterin bereitetes Androsteron," Zeitschrift für physiologische Chemie, Band 233 (1935), pp. 281-83.

First Known Use

1935, in the meaning defined at sense 1

Rhymes for testosterone

• aldosterone
• anticyclone
• progesterone
• acetone
• anglophone
• baritone
• bourguignon
• buspirone
• chaperon
• chaperone
• cobblestone
• collarbone

Kids Definition

testosterone

noun

tes·​tos·​ter·​one te-ˈstäs-tə-ˌrōn 

: a male hormone produced by the testes that causes the development of the male reproductive system and secondary sex characteristics

Medical Definition

testosterone

noun

tes·​tos·​ter·​one te-ˈstäs-tə-ˌrōn 

: a male hormone that is a crystalline hydroxy steroid ketone C₁₉H₂₈O₂ produced primarily by the testes or made synthetically and that is the main androgen responsible for inducing and maintaining male secondary sex characteristics see androgel, axiron