Definition of progesterone
: a female steroid sex hormone C21H30O2 that is secreted by the corpus luteum to prepare the endometrium for implantation and later by the placenta during pregnancy to prevent rejection of the developing embryo or fetus
also
: a synthetic steroid resembling progesterone in action
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Merriam-Webster unabridged
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Time Traveler for progesterone
The first known use of progesterone was in 1935
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