progestin

noun

pro·​ges·​tin prō-ˈje-stən 

: a synthetic progestogen (such as levonorgestrel)

Examples of progestin in a Sentence

Recent Examples on the Web

IUDs are also an option, as well as therapies that combine estrogen with progestin, such as pills or patches. — Cathy Nelson, Health, 1 July 2026

Hormone replacement therapy − estrogen often coupled with progestin − is the preferred treatment for menopause, according to The Menopause Society. — Laura Trujillo, USA Today, 6 May 2026

The authors’ primary evidence of harm is from the 2002 WHI study, which studied conjugated equine estrogen and synthetic progestin in women averaging 63 years old, more than a decade past menopause. — Torie Bosch, STAT, 2 May 2026

In addition, higher protein levels in the blood were a stronger predictor of dementia risk in women who took hormone therapy for menopause combining both estrogen and progestin than in women who didn’t use hormones. — Emily Kay Votruba, EverydayHealth.com, 10 Mar. 2026

Word History

Etymology

progest(ational) + -in entry 1, originally as a name for progesterone

Note: The name was introduced by the American gynecologist and biochemist Willard M. Allen (1904-93) in "Physiology of the Corpus Luteum V. The Preparation and Some Chemical Properties of Progestin, a Hormone of the Corpus Luteum which Produces Progestational Proliferation," Amerian Journal of Physiology, vol. 92, issue 1 (February, 1930), pp. 174-88.

First Known Use

1945, in the meaning defined above

Rhymes for progestin

• clandestine
• intestine

Medical Definition

progestin

noun

pro·​ges·​tin prō-ˈjest-ən 

: a synthetic progestogen (such as levonorgestrel)