antibody

noun

an·​ti·​body ˈan-ti-ˌbä-dē How to pronounce antibody (audio)
: any of a large number of proteins of high molecular weight that are produced normally by specialized B cells after stimulation by an antigen and act specifically against the antigen in an immune response, that are produced abnormally by some cancer cells, and that typically consist of four subunits including two heavy chains and two light chains

called also immunoglobulin

Examples of antibody in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Summit Therapeutics said the FDA accepted its application seeking approval of its PD-1/VEGF antibody ivonescimab to treat non-small cell lung cancer. Meghana Keshavan, STAT, 29 Jan. 2026 However, scientists discovered an antibody called MAD21-101 that is precise enough to catch it. Kwesi Akonu Adom Mensah Forson, The Conversation, 26 Jan. 2026 Samples from the 28 children showed that 25 of them were carrying these antibodies. Jon Hamilton, NPR, 22 Jan. 2026 Even an antibody test wouldn’t be able to differentiate between the donor receiving the vaccine and having antibodies from having COVID-19, Crawford said. Emma Murphy, Oklahoma Voice, 21 Jan. 2026 See All Example Sentences for antibody

Word History

First Known Use

1894, in the meaning defined above

Time Traveler
The first known use of antibody was in 1894

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Cite this Entry

“Antibody.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/antibody. Accessed 3 Feb. 2026.

Kids Definition

antibody

noun
an·​ti·​body ˈant-i-ˌbäd-ē How to pronounce antibody (audio)
: a substance produced by special cells of the body that combines with an antigen and counteracts its effects or those of the microscopic plant or animal on which the antigen may occur

Medical Definition

antibody

noun
an·​ti·​body ˈant-i-ˌbäd-ē How to pronounce antibody (audio)
plural antibodies
: any of a large number of proteins of high molecular weight that are produced normally by specialized B cells after stimulation by an antigen and act specifically against the antigen in an immune response, that are produced abnormally by some cancer cells, and that typically consist of four subunits including two heavy chains and two light chains

called also immunoglobulin

More from Merriam-Webster on antibody

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