hydrocodone

noun

hy·​dro·​co·​done ˌhī-drō-ˈkō-ˌdōn How to pronounce hydrocodone (audio)
: a habit-forming compound that is derived from codeine and is administered in the form of its bitartrate C18H21NO3·C4H6O6 usually in combination with other drugs (as acetaminophen) as an analgesic or cough suppressant

Examples of hydrocodone in a Sentence

Recent Examples on the Web
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The pills were later determined to be the painkiller hydrocodone, according to the affidavit. Emily Mae Czachor, CBS News, 3 Apr. 2026 Police reported finding two hydrocodone pills in the 50-year-old Presidential Medal of Freedom winner’s pockets when he was searched at the crash site. Brian Niemietz, New York Daily News, 3 Apr. 2026 An arrest affidavit noted that Woods allegedly carried two hydrocodone pills in his left pocket following the crash. Sydney Topf, The Washington Examiner, 3 Apr. 2026 Woods had two white pills in his pocket at the time of his arrest, which were later identified as the opioid hydrocodone, per the affidavit. Emlyn Travis, Entertainment Weekly, 3 Apr. 2026 See All Example Sentences for hydrocodone

Word History

First Known Use

1964, in the meaning defined above

Time Traveler
The first known use of hydrocodone was in 1964

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Cite this Entry

“Hydrocodone.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/hydrocodone. Accessed 9 Apr. 2026.

Medical Definition

hydrocodone

noun
hy·​dro·​co·​done ˌhī-drō-ˈkō-ˌdōn How to pronounce hydrocodone (audio)
: a habit-forming compound derived from codeine and administered in the form of its bitartrate C18H21NO3·C4H6O6 usually in combination with other drugs (as acetaminophen) as an analgesic or cough sedative

called also dihydrocodeinone

see hycodan, vicodin
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