annoy implies a wearing on the nerves by persistent petty unpleasantness.
their constant complaining annoys us
vex implies greater provocation and stronger disturbance and usually connotes anger but sometimes perplexity or anxiety.
vexed by her son's failure to clean his room
irk stresses difficulty in enduring and the resulting weariness or impatience of spirit.
careless waste irks the boss
bother suggests interference with comfort or peace of mind.
don't bother me while I'm reading
Examples of vex in a Sentence
This problem has vexed researchers for years.
We were vexed by the delay.
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The film isn’t interested in the ethical issues of a boss sleeping with her underling or how exactly Jackie garnered such a vexing reputation.—Angelica Jade Bastién, Vulture, 8 June 2026 Repairs cost companies and communities, vex corporate executives and politicians and tax work crews.—John Ruwitch, NPR, 3 June 2026 Until these vexing unknowns are figured out, AI for mental health will be in an uneasy position and subject to strident criticisms and concerns.—Lance Eliot, Forbes.com, 1 June 2026 Gray said the strikeout issue has been vexing, but he was encouraged by Wednesday’s progress.—Mac Cerullo, Boston Herald, 14 May 2026 See All Example Sentences for vex
Word History
Etymology
Middle English, from Anglo-French vexer, from Latin vexare to agitate, harry; probably akin to Latin vehere to convey — more at way