molecule

noun

mol·​e·​cule ˈmä-li-ˌkyül How to pronounce molecule (audio)
Synonyms of moleculenext
1
: the smallest particle of a substance that retains all the properties (see property sense 1a) of the substance and is composed of one or more atoms (see atom sense 1a)
a molecule of water
a molecule of oxygen
2
: a tiny bit : particle
There is a molecule of evidence to support these charges.

Examples of molecule in a Sentence

There is not a molecule of evidence to support these charges. not a molecule of sense in that girl
Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
In addition, the peptide seems to promote angiogenesis, the development of new blood vessels, possibly via a signalling molecule expressed in many human cancers. Dhruv Khullar, New Yorker, 6 Apr. 2026 Research shows the area releases millions of particles, aerosols and molecules of dangerous pollutants into the air — including hydrogen sulfide, which has twice spiked to record levels in the last two weeks, according to data from the San Diego County Air Pollution Control District. Walker Armstrong, San Diego Union-Tribune, 5 Apr. 2026 The process causes a violent compression of air molecules that can heat the spacecraft’s exterior to more than 5,000 degrees Fahrenheit (2,760 degrees Celsius). Jackie Wattles, CNN Money, 3 Apr. 2026 In muscle cells myosin molecules assemble into thick filaments through interactions among their tail regions. Encyclopedia Britannica, 3 Apr. 2026 See All Example Sentences for molecule

Word History

Etymology

French molécule, from New Latin molecula, diminutive of Latin moles mass

First Known Use

1701, in the meaning defined at sense 1

Time Traveler
The first known use of molecule was in 1701

Browse Nearby Words

Cite this Entry

“Molecule.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/molecule. Accessed 7 Apr. 2026.

Kids Definition

molecule

noun
mol·​e·​cule ˈmäl-i-ˌkyü(ə)l How to pronounce molecule (audio)
1
: the smallest particle of a substance having all the characteristics of the substance
a molecule of water
a molecule of oxygen
2
: a very small bit : particle

Medical Definition

molecule

noun
mol·​e·​cule ˈmäl-i-ˌkyü(ə)l How to pronounce molecule (audio)
: the smallest particle of a substance that retains all the properties of the substance and is composed of one or more atoms

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