lesion

noun

le·​sion ˈlē-zhən How to pronounce lesion (audio)
1
2
: an abnormal change in structure of an organ or part due to injury or disease
especially : one that is circumscribed (see circumscribe sense 1) and well defined
lesioned adjective

Examples of lesion in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Within his first year at the front, Malaparte was exposed to mustard gas, leaving a pulmonary lesion that, nearly forty years later, contributed to his death. Thomas Meaney, New Yorker, 2 July 2025 Gross necropsy showed lesions in Kota's brain which indicated diffuse encephalopathy, or widespread dysfunction of the brain and brain hemorrhaging, the zoo said. Harley Walls, Arkansas Online, 28 June 2025 My appendix was removed, along with another 14 lesions (after having 37 endometriosis lesions and a cyst removed two years ago). Vanessa Etienne, People.com, 28 May 2025 But about five months before his visit to the emergency department, one of the lesions on his left ankle had progressed to an ulcer. ArsTechnica, 3 July 2025 See All Example Sentences for lesion

Word History

Etymology

Middle English, from Anglo-French, from Latin laesion-, laesio, from laedere to injure

First Known Use

15th century, in the meaning defined at sense 1

Time Traveler
The first known use of lesion was in the 15th century

Browse Nearby Words

Cite this Entry

“Lesion.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/lesion. Accessed 24 Jul. 2025.

Kids Definition

lesion

noun
le·​sion ˈlē-zhən How to pronounce lesion (audio)
: a change in the structure of a bodily organ or part due to injury or disease
especially : an injured or diseased spot or area clearly marked off from healthy tissue around it

Medical Definition

lesion

1 of 2 noun
le·​sion ˈlē-zhən How to pronounce lesion (audio)
: an abnormal change in structure of an organ or part due to injury or disease
especially : one that is circumscribed and well defined
lesioned adjective

lesion

2 of 2 transitive verb
: to produce lesions in (as an animal's brain)

Legal Definition

lesion

noun
le·​sion ˈlē-zhən How to pronounce lesion (audio)
in the civil law of Louisiana : loss from failure to receive a threshold amount or value (as one-half market value) for immovable property conveyed or transferred by a commutative contract (as a sale or exchange)

called also lesion beyond moiety

compare unjust enrichment
Etymology

Anglo-French, damage, injury, from Latin laesio, from laedere to injure

More from Merriam-Webster on lesion

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