2
: an abnormal change in structure of an organ or part due to injury or disease
especially
: one that is circumscribed (see circumscribe sense 1) and well defined
Examples of lesion in a Sentence
Recent Examples on the Web
It was successfully treated but the parasite caused permanent brain lesions leading to gradual degeneration that affected her coordination, mobility, and motor skills.
—
Pioneer Press, Twin Cities, 16 Apr. 2025
Now a new study published in the journal Neurology has found that having eight or more alcoholic drinks per week raises the risk of developing brain lesions — areas of abnormal or damaged tissue associated with dementia.
—Tom Gavin, EverydayHealth.com, 10 Apr. 2025
All of these people might have weaker immune systems or are more prone to skin sores or lesions—a main risk factor for invasive strep.
—Alice Park, Time, 10 Apr. 2025
Scientists examined their brain tissue to look for signs of brain injury, including a lesion called hyaline arteriolosclerosis, which is associated with memory and cognitive problems, and tau tangles, which are associated with Alzheimer’s disease.
—Katia Hetter, CNN Money, 9 Apr. 2025
See All Example Sentences for lesion
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Pioneer Press, Twin Cities, 16 Apr. 2025
Now a new study published in the journal Neurology has found that having eight or more alcoholic drinks per week raises the risk of developing brain lesions — areas of abnormal or damaged tissue associated with dementia.
—Tom Gavin, EverydayHealth.com, 10 Apr. 2025
All of these people might have weaker immune systems or are more prone to skin sores or lesions—a main risk factor for invasive strep.
—Alice Park, Time, 10 Apr. 2025
Scientists examined their brain tissue to look for signs of brain injury, including a lesion called hyaline arteriolosclerosis, which is associated with memory and cognitive problems, and tau tangles, which are associated with Alzheimer’s disease.
—Katia Hetter, CNN Money, 9 Apr. 2025
See All Example Sentences for lesion
Cite this Entry
“Lesion.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/lesion. Accessed 6 May. 2025.
Copy CitationKids Definition
lesion
noun
le·sion
ˈlē-zhən 
: a change in the structure of a bodily organ or part due to injury or disease
especially
: an injured or diseased spot or area clearly marked off from healthy tissue around it
Medical Definition
Legal Definition
lesion
noun
le·sion
ˈlē-zhən
in the civil law of Louisiana
: loss from failure to receive a threshold amount or value (as one-half market value) for immovable property conveyed or transferred by a commutative contract (as a sale or exchange)
called also lesion beyond moiety
compare unjust enrichmentEtymology
Anglo-French, damage, injury, from Latin laesio, from laedere to injure
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