2
: an abnormal change in structure of an organ or part due to injury or disease
especially
: one that is circumscribed (see circumscribe sense 1) and well-defined
Examples of lesion in a Sentence
Recent Examples on the Web
Without adequate blood supply, the skin takes on the appearance of lesions at the injection site and throughout the body.
—
Anna Giaritelli, The Washington Examiner, 17 May 2026
The endometriosis was so extensive that my abdomen was drowning in lesions, scar tissue, and adhesions.
—Nami Mun, The Atlantic, 16 May 2026
What makes this especially remarkable is the evidence from lesion studies.
—Scott Travers, Forbes.com, 16 May 2026
This is also linked to a change known as Darier’s sign, which is a common finding in mastocytosis, where rubbing a skin lesion causes redness or swelling.
—Suchandrima Bhowmik, Health, 15 May 2026
See All Example Sentences for lesion
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Anna Giaritelli, The Washington Examiner, 17 May 2026
The endometriosis was so extensive that my abdomen was drowning in lesions, scar tissue, and adhesions.
—Nami Mun, The Atlantic, 16 May 2026
What makes this especially remarkable is the evidence from lesion studies.
—Scott Travers, Forbes.com, 16 May 2026
This is also linked to a change known as Darier’s sign, which is a common finding in mastocytosis, where rubbing a skin lesion causes redness or swelling.
—Suchandrima Bhowmik, Health, 15 May 2026
See All Example Sentences for lesion
Cite this Entry
“Lesion.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/lesion. Accessed 18 May. 2026.
Copy CitationKids Definition
lesion
noun
le·sion
ˈlē-zhən 
: a change in the structure of a bodily organ or part due to injury or disease
especially
: an injured or diseased spot or area clearly marked off from healthy tissue around it
Medical Definition
Legal Definition
lesion
noun
le·sion
ˈlē-zhən
in the civil law of Louisiana
: loss from failure to receive a threshold amount or value (as one-half market value) for immovable property conveyed or transferred by a commutative contract (as a sale or exchange)
called also lesion beyond moiety
compare unjust enrichmentEtymology
Anglo-French, damage, injury, from Latin laesio, from laedere to injure
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