2
: an abnormal change in structure of an organ or part due to injury or disease
especially
: one that is circumscribed (see circumscribe sense 1) and well-defined
Examples of lesion in a Sentence
Recent Examples on the Web
Patients may develop more widespread skin rashes rather than a single bull's-eye lesion, and some infections have required hospitalization.
—
Moná Thomas, PEOPLE, 11 June 2026
White larva may also be visible within the skin lesions, Hohenhaus said.
—Julia Jacobo, ABC News, 11 June 2026
The hero ingredient, noni extract, helps heal skin lesions, restores the barrier function, and can even help boost the immune system.
—Alyssa Morin, InStyle, 11 June 2026
The telltale signs of a screwworm infection are the growing wounds or lesions and the presence of feeding maggots on still-alive animals.
—Mateo Rosiles, USA Today, 9 June 2026
See All Example Sentences for lesion
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Moná Thomas, PEOPLE, 11 June 2026
White larva may also be visible within the skin lesions, Hohenhaus said.
—Julia Jacobo, ABC News, 11 June 2026
The hero ingredient, noni extract, helps heal skin lesions, restores the barrier function, and can even help boost the immune system.
—Alyssa Morin, InStyle, 11 June 2026
The telltale signs of a screwworm infection are the growing wounds or lesions and the presence of feeding maggots on still-alive animals.
—Mateo Rosiles, USA Today, 9 June 2026
See All Example Sentences for lesion
Cite this Entry
“Lesion.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/lesion. Accessed 16 Jun. 2026.
Copy CitationKids Definition
lesion
noun
le·sion
ˈlē-zhən 
: a change in the structure of a bodily organ or part due to injury or disease
especially
: an injured or diseased spot or area clearly marked off from healthy tissue around it
Medical Definition
Legal Definition
lesion
noun
le·sion
ˈlē-zhən
in the civil law of Louisiana
: loss from failure to receive a threshold amount or value (as one-half market value) for immovable property conveyed or transferred by a commutative contract (as a sale or exchange)
called also lesion beyond moiety
compare unjust enrichmentEtymology
Anglo-French, damage, injury, from Latin laesio, from laedere to injure
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