2
: an abnormal change in structure of an organ or part due to injury or disease
especially
: one that is circumscribed (see circumscribe sense 1) and well-defined
Examples of lesion in a Sentence
Recent Examples on the Web
Woodland suffers from severe anxiety and post-traumatic stress disorder, having endured a series of personal trials and tragedies, including a brain lesion that was affecting his mental health.
—
Don Riddell, CNN Money, 9 Apr. 2026
After examining his right hip, doctors found that a cam lesion on the head of Brossoit’s femur was causing the problem.
—Curtis Pashelka, Mercury News, 8 Apr. 2026
Recluse spider lesions can be misdiagnosed due to their similarity to sores from bacteria such as methicillin-resistant Staphylococcus.
—Matthew Cordes, The Conversation, 6 Apr. 2026
Just two weeks ago, Gary Woodland decided ot shared his struggles with post traumatic stress disorder, brought on after a September 2023 surgery, which involved a baseball-sized hole cut from the side of his head, to remove a brain lesion.
—Andrew McCarty, MSNBC Newsweek, 31 Mar. 2026
See All Example Sentences for lesion
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Don Riddell, CNN Money, 9 Apr. 2026
After examining his right hip, doctors found that a cam lesion on the head of Brossoit’s femur was causing the problem.
—Curtis Pashelka, Mercury News, 8 Apr. 2026
Recluse spider lesions can be misdiagnosed due to their similarity to sores from bacteria such as methicillin-resistant Staphylococcus.
—Matthew Cordes, The Conversation, 6 Apr. 2026
Just two weeks ago, Gary Woodland decided ot shared his struggles with post traumatic stress disorder, brought on after a September 2023 surgery, which involved a baseball-sized hole cut from the side of his head, to remove a brain lesion.
—Andrew McCarty, MSNBC Newsweek, 31 Mar. 2026
See All Example Sentences for lesion
Cite this Entry
“Lesion.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/lesion. Accessed 12 Apr. 2026.
Copy CitationKids Definition
lesion
noun
le·sion
ˈlē-zhən 
: a change in the structure of a bodily organ or part due to injury or disease
especially
: an injured or diseased spot or area clearly marked off from healthy tissue around it
Medical Definition
Legal Definition
lesion
noun
le·sion
ˈlē-zhən
in the civil law of Louisiana
: loss from failure to receive a threshold amount or value (as one-half market value) for immovable property conveyed or transferred by a commutative contract (as a sale or exchange)
called also lesion beyond moiety
compare unjust enrichmentEtymology
Anglo-French, damage, injury, from Latin laesio, from laedere to injure
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