zi·​do·​vu·​dine zi-ˈdō-vyü-ˌdēn How to pronounce zidovudine (audio)
: azt

Examples of zidovudine in a Sentence

Recent Examples on the Web This is not a new concept, as it was implemented more than 30 years ago for zidovudine (azidothymidine), the first drug approved for HIV. Mark J. Ratain, STAT, 15 Aug. 2023 Infected case patients were significantly less likely to have taken zidovudine than uninfected controls (odds ratio 0.19, P=0.003). Neuroskeptic, Discover Magazine, 5 Apr. 2012 By univariate analysis, there was no significant difference between case patients and controls in the use of zidovudine [AZT, the first HIV drug] after exposure. Neuroskeptic, Discover Magazine, 5 Apr. 2012 In the early 1990s, the drug development and regulatory landscape for new AIDS therapies was bleak: no new drugs had been approved since the first antiretroviral therapy, zidovudine (also known as AZT) in 1987. Emil D. Kakkis, STAT, 7 July 2021 In 1987, for example, the cancer drug zidovudine became the first F.D.A.-approved drug against H.I.V. The most obvious drugs to repurpose against the new coronavirus are those that work against other viruses. Carl Zimmer, New York Times, 30 Apr. 2020 Until recently only two drugs – zidovudine and lamivudine – have had adequate safety and dosing data from birth. Gbolahan Ajibola, The Conversation, 27 Nov. 2019 Shortly after his diagnosis seven years earlier, Dan started taking high doses of AZT (zidovudine, the first antiretroviral drug approved by the FDA in 1987) as a part of his treatment protocol. S. Kirk Walsh, Longreads, 22 Jan. 2018

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'zidovudine.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History


by shortening & alteration from azidothymidine

First Known Use

1987, in the meaning defined above

Time Traveler
The first known use of zidovudine was in 1987

Dictionary Entries Near zidovudine

Cite this Entry

“Zidovudine.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/zidovudine. Accessed 17 Apr. 2024.

Medical Definition


zi·​do·​vu·​dine zī-ˈdō-v(y)ü-ˌdēn How to pronounce zidovudine (audio)
: azt
Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!