tre·​tin·​o·​in | \tre-ˈti-nə-win \

Definition of tretinoin 

: the all-trans isomer of retinoic acid that is applied to the skin to treat severe acne and reduce facial wrinkles, roughness, and pigmented spots

Examples of tretinoin in a Sentence

Recent Examples on the Web

As a refresher, most wrinkle creams are filled with your classic retinol or tretinoin, two of the strongest (and potentially irritating) topical retinoids. Chloe Metzger, Marie Claire, "The 5 Truly Excellent Beauty Products I'm Loving This Week," 10 Oct. 2018 Stop using skincare products with harsh ingredients, including glycolic and salicylic acids, benzoyl peroxide, and any retinoids (including tretinoin and adapalene), at least five days before your treatment. Deanna Pai, Glamour, "The Brown Girl's Guide to Laser Hair Removal," 20 Aug. 2018 Night cream + retinol: Lortscher says that your nightly retinol application can come in the form of creams with over-the-counter retinol or a prescription retinoid, such as tretinoin. Adam Hurly, GQ, "How to Fix Your Dehydrated Skin," 3 July 2018 Retinol and tretinoin should only be used at night. Dr. Leslie Baumann, miamiherald, "What you need to know about 'hazardous' sunscreen ingredients | Miami Herald," 27 Apr. 2018 Bottom line: The vitamin A derivatives known as retinol, tretinoin, adapalene, and tazarotene can protect the skin from sun damage. Dr. Leslie Baumann, miamiherald, "What you need to know about 'hazardous' sunscreen ingredients | Miami Herald," 27 Apr. 2018 But the recent proliferation of various AHA, BHA, and PHA acids and ceramide, niacinamide, and tretinoin creams in my medicine cabinet suggests otherwise. Lisa Haney, The Cut, "What It’s Like to Break Your Face Like Carrie Underwood," 16 Apr. 2018 Pimples can be treated with skin-care products containing acne-fighting ingredients, like bacteria-killing benzoyl peroxide and exfoliating salicylic acid, as well as topical retinoids like tretinoin, adapalene, or tazarotene. Kaleigh Fasanella, Allure, "How to Tell If Your Little Red Facial Bump Is a Pimple or a Cold Sore," 26 Feb. 2018 Prescription topicals such as tazarotene and tretinoin creams have been shown to reduce fine-line wrinkles, skin roughness and sun and age spots. Consumer Reports, Washington Post, "Little evidence for supplements to treat thinning hair, dry skin and brittle nails," 7 Aug. 2017

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'tretinoin.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of tretinoin

1970, in the meaning defined above

History and Etymology for tretinoin

perhaps from trans- + retinoic acid

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Last Updated

13 Nov 2018

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Time Traveler for tretinoin

The first known use of tretinoin was in 1970

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tre·​tin·​o·​in | \tre-ˈtin-ə-wən \

Medical Definition of tretinoin 

: the all-trans isomer of retinoic acid that is applied topically to the skin to treat acne vulgaris and to reduce facial wrinkles, roughness, and pigmented spots and that is administered orally to induce remission of acute myelogenous leukemia in which more than half the cells are malignant promyelocytes

called also all-trans-retinoic acid, retinoic acid, vitamin A acid

— see isotretinoin, retin-a

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