tre·​tin·​o·​in | \ tre-ˈti-nə-win How to pronounce tretinoin (audio) \

Definition of tretinoin

: the all-trans isomer of retinoic acid that is applied to the skin to treat severe acne and reduce facial wrinkles, roughness, and pigmented spots

Examples of tretinoin in a Sentence

Recent Examples on the Web Kligman pioneered numerous treatments for acne and skin issues, including his discovery that tretinoin, a retinoic acid and Vitamin A derivative, could improve acne and other skin issues related to aging, like wrinkles. Popular Science, "This popular acne medication carries a disturbing legacy," 7 Dec. 2020 Prescription-grade retinoid treatments can be topical (applied to your skin), such as adapalene 0.3-percent gel, tretinoin, tazarotene and trifarotene. Nicole Saunders, NBC News, "11 Best retinol creams and retinol serums for acne and wrinkles," 23 Oct. 2020 Then there’s the prescription version which is pure tretinoin. Nicole Catanese, Good Housekeeping, "Ask an Expert: How Do I Start a Retinol Routine?," 18 Sep. 2020 In skincare, retinol is an OTC version of prescription-strength tretinoin, also known as retinoic acid, which is often prescribed by dermatologists for acne treatment and anti-aging purposes, according to Dr. Lee. Danusia Wnek, Good Housekeeping, "What Is Retinol? Facts About Its Uses, Benefits, and Side Effects," 23 Aug. 2020 Retinoid is typically used to describe prescription-strength retinoid products, such as tretinoin and tazarotene, which have retinoic acid. Deanna Pai, Glamour, "Retinoid vs. Retinol: When to Use Each and Why," 25 June 2020 Vitamin A and its various derivatives are called retinoids, and these ingredients can range from low-concentration treatments like Differin gel to prescription-strength Retin-A or tretinoin. Nia Decaille, Washington Post, "A guide to the confusing and sometimes controversial ingredients in your cosmetics," 7 Feb. 2020 And prescription-only retinoid acid, or tretinoin (Retin-A), is more effective, yet harsher on the skin. Dina Cheney, SELF, "Here's Exactly How and When to Use 5 Basic Skin-Care Staples," 4 Oct. 2019 Retinoids: Retinol, retinal, tretinoin, and the like are all topical retinoids, which are forms of vitamin A. These can speed up the skin’s cell turnover process, Stevenson explains, which helps treat acne as well as signs of aging, like fine lines. Sarah Jacoby, SELF, "PSA: It’s Totally Fine and Normal to Have Visible Pores on Your Face," 23 July 2019

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'tretinoin.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of tretinoin

1970, in the meaning defined above

History and Etymology for tretinoin

perhaps from trans- + retinoic acid

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Time Traveler for tretinoin

Time Traveler

The first known use of tretinoin was in 1970

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Cite this Entry

“Tretinoin.” Dictionary, Merriam-Webster, Accessed 2 Mar. 2021.

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tre·​tin·​o·​in | \ tre-ˈtin-ə-wən How to pronounce tretinoin (audio) \

Medical Definition of tretinoin

: the all-trans isomer of retinoic acid that is applied topically to the skin to treat acne vulgaris and to reduce facial wrinkles, roughness, and pigmented spots and that is administered orally to induce remission of acute myelogenous leukemia in which more than half the cells are malignant promyelocytes

called also all-trans-retinoic acid, retinoic acid, vitamin A acid

— see isotretinoin, retin-a

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