isotretinoin

noun
iso·​tret·​i·​noin | \ ˌī-sō-ˈtre-tə-ˌnȯin How to pronounce isotretinoin (audio) \

Definition of isotretinoin

: a cis isomer of retinoic acid that is a synthetic derivative of vitamin A, inhibits sebaceous gland function and keratinization, and is used in the treatment of severe inflammatory acne but is contraindicated in pregnancy because of its implication as a cause of birth defects

Examples of isotretinoin in a Sentence

Recent Examples on the Web For severe acne that’s prone to scarring, oral isotretinoin (a.k.a., Accutane) may be an option. Stacey Colino, Washington Post, 21 June 2022 The cause, in most cases, is unknown, although some cases are caused by genetic changes or the use of isotretinoin, or Accutane medication, during pregnancy. Li Cohen, CBS News, 2 June 2022 These precautions are intense, but dermatologists agree that the final results for isotretinoin are like no other. Sarah Jacoby, SELF, 27 Dec. 2021 Accutane, aka isotretinoin, is a powerful medication used to treat a particular type of severe acne known as recalcitrant nodular acne, according to the US National Library of Medicine's MedlinePlus resource. Korin Miller, Health.com, 20 May 2021 And Accutane — a drug used to treat severe acne — is actually an oral vitamin A called isotretinoin. Julie Ricevuto, Allure, 12 Nov. 2020 They can also be taken orally, including isotretinoin for acne and acitretin to treat psoriasis. Nicole Saunders, NBC News, 23 Oct. 2020 Over-the-counter retinoids are available in almost every product form imaginable, while most prescription forms are a cream or gel, besides isotretinoin (commonly known as Accutane), which is taken orally. Caroline Solomon, Glamour, 10 Apr. 2020 Over the counter retinoids are available in almost every product form imaginable, while most prescription forms are a cream or gel, besides isotretinoin (commonly known as Accutane), which is taken orally. Caroline Solomon, Glamour, 6 Dec. 2019 See More

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'isotretinoin.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

First Known Use of isotretinoin

1979, in the meaning defined above

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The first known use of isotretinoin was in 1979

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Last Updated

30 Jun 2022

Cite this Entry

“Isotretinoin.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/isotretinoin. Accessed 6 Jul. 2022.

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More Definitions for isotretinoin

isotretinoin

noun
iso·​tret·​i·​noin | \ ˌī-sō-ˈtret-ə-ˌnȯin How to pronounce isotretinoin (audio) \

Medical Definition of isotretinoin

: a cis isomer of retinoic acid that is a synthetic derivative of vitamin A, that inhibits sebaceous gland function and keratinization, and that is administered in the treatment of severe inflammatory acne but is contraindicated in pregnancy because of its implication as a cause of birth defects

called also 13-cis-retinoic acid, retinoic acid

— see accutane

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