isotretinoin

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noun iso·tret·i·noin \ ˌī-sō-ˈtre-tə-ˌnȯin \

Definition of isotretinoin

:a cis isomer of retinoic acid that is a synthetic derivative of vitamin A, inhibits sebaceous gland function and keratinization, and is used in the treatment of severe inflammatory acne

First Known Use of isotretinoin

1979


Medical Dictionary

isotretinoin

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noun iso·tret·i·noin \ ˌī-sō-ˈtret-ə-ˌnȯin \

medical Definition of isotretinoin

:a cis isomer of retinoic acid that is a synthetic derivative of vitamin A, that inhibits sebaceous gland function and keratinization, and that is administered in the treatment of severe inflammatory acne but is contraindicated in pregnancy because of its implication as a cause of birth defects called also 13-cis-retinoic acid, retinoic acid; see accutane

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