isotretinoin

noun
iso·​tret·​i·​noin | \ ˌī-sō-ˈtre-tə-ˌnȯin How to pronounce isotretinoin (audio) \

Definition of isotretinoin

: a cis isomer of retinoic acid that is a synthetic derivative of vitamin A, inhibits sebaceous gland function and keratinization, and is used in the treatment of severe inflammatory acne but is contraindicated in pregnancy because of its implication as a cause of birth defects

Examples of isotretinoin in a Sentence

Recent Examples on the Web And Accutane — a drug used to treat severe acne — is actually an oral vitamin A called isotretinoin. Julie Ricevuto, Allure, "The Science of Beauty: The Complete Guide to Vitamins for Skin Health," 12 Nov. 2020 They can also be taken orally, including isotretinoin for acne and acitretin to treat psoriasis. Nicole Saunders, NBC News, "11 Best retinol creams and retinol serums for acne and wrinkles," 23 Oct. 2020 Over-the-counter retinoids are available in almost every product form imaginable, while most prescription forms are a cream or gel, besides isotretinoin (commonly known as Accutane), which is taken orally. Caroline Solomon, Glamour, "What Is Retinol and How Do You Use It?," 10 Apr. 2020 Over the counter retinoids are available in almost every product form imaginable, while most prescription forms are a cream or gel, besides isotretinoin (commonly known as Accutane), which is taken orally. Caroline Solomon, Glamour, "What Is Retinol and How Do You Use It?," 6 Dec. 2019 Going on isotretinoin is a serious undertaking that involves pregnancy tests and flaky skin. Bella Cacciatore, Glamour, "9 Things I Wish I’d Known Before Starting Accutane," 28 Aug. 2019 For example, retinoids such as tretinoin and isotretinoin are a no-no during pregnancy because they have been linked to birth defects. Nikhita Mahtani, SELF, "How to Safely Treat Your Postpartum Acne," 24 Apr. 2019 But mental health effects from isotretinoin are now being cited in the trial of a 15-year-old charged with first-degree murder and 10 other counts in the alleged stabbing of a 20-year-old woman in Colorado last year. Macaela Mackenzie, Allure, "Isotretinoin, the Drug Formerly Known as Accutane, May Be Cited in Upcoming Murder Trial," 2 Mar. 2018 This isn't the first time the finger has been pointed at the link between isotretinoin and mental health in a court case. Zoë Weiner, Teen Vogue, "Acne Drug Commonly Known as Accutane May Be Cited in a Murder Case," 2 Mar. 2018

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'isotretinoin.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of isotretinoin

1979, in the meaning defined above

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Time Traveler for isotretinoin

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The first known use of isotretinoin was in 1979

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Cite this Entry

“Isotretinoin.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/isotretinoin. Accessed 26 Feb. 2021.

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More Definitions for isotretinoin

isotretinoin

noun
iso·​tret·​i·​noin | \ ˌī-sō-ˈtret-ə-ˌnȯin How to pronounce isotretinoin (audio) \

Medical Definition of isotretinoin

: a cis isomer of retinoic acid that is a synthetic derivative of vitamin A, that inhibits sebaceous gland function and keratinization, and that is administered in the treatment of severe inflammatory acne but is contraindicated in pregnancy because of its implication as a cause of birth defects

called also 13-cis-retinoic acid, retinoic acid

— see accutane

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