naloxone

noun
nal·​ox·​one | \ na-ˈläk-ˌsōn How to pronounce naloxone (audio) \

Definition of naloxone

: a synthetic potent antagonist of narcotic drugs (such as morphine and fentanyl) that is administered especially in the form of its hydrochloride C19H21NO4·HCl

Note: Naloxone is administered by injection or as a nasal spray to reverse the effects of opioids especially in the emergency treatment of opioid overdose. It is also administered in combination with buprenorphine in the form of a dissolvable tablet placed under the tongue or a film placed inside the cheek to treat opioid dependence.

Examples of naloxone in a Sentence

Recent Examples on the Web People can also complete an online naloxone program. al, "Drug overdoses climbed in Alabama during pandemic," 25 Jan. 2021 Expanding locations in which overdose prevention education and take-home naloxone are provided, especially in rural areas is important, the CDC said. Mallika Kallingal And Maggie Fox, CNN, "CDC warns of a 'substantial increase' in fatal drug overdoses coinciding with the Covid-19 pandemic," 18 Dec. 2020 For reducing overdoses, advocates distribute the overdose-reversing medication naloxone and encourage people not to use drugs alone. John Keilman, chicagotribune.com, "Can harm reduction, the philosophy that stems HIV transmission and heroin overdoses, help curb a Thanksgiving COVID-19 meltdown?," 21 Nov. 2020 Regarding black-market drugs, such a system would include needle-exchange programs and dissemination of the overdose-reversing drug naloxone. Sally Satel, WSJ, "‘White Market Drugs’ Review: Addiction by Prescription," 20 Oct. 2020 Used as a guide for distributing limited resources, like naloxone and fentanyl testing strips, the initiative seems to be working, according to the first annual report released Wednesday by the Department of Public Health. Rebecca Lurye, courant.com, "First report on Connecticut’s real-time, opioid overdose tracking system reveals higher number of cases in Hartford County," 24 Sep. 2020 Nationally, overdoses are estimated to have risen 18% during the pandemic, and these incidents are more dangerous now that people are isolated, with no one nearby to administer naloxone or call an ambulance. STAT, "Pregnancy poses challenges for people in recovery from substance use disorder. Covid-19 is taxing their support system," 10 Sep. 2020 Pfizer donated 1 million doses of injectable naloxone to Direct Relief, which shipped the doses to its network of providers. Ken Alltucker, USA TODAY, "Clinton Foundation works to put naloxone in recovery homes as opioid epidemic is overshadowed by COVID pandemic," 31 Aug. 2020 Amid reports of an increase in opioid overdose deaths and a rise in the use of naloxone, employers are asking for help about the best and safest strategies for bringing workers back to the manufacturing floor or office, Pferrer said. Shari Rudavsky, The Indianapolis Star, "'There is no playbook' on how to handle what we all have: pandemic fatigue," 4 Sep. 2020

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'naloxone.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of naloxone

1964, in the meaning defined above

History and Etymology for naloxone

N-allyl + hydroxy- + -one

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Time Traveler for naloxone

Time Traveler

The first known use of naloxone was in 1964

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Cite this Entry

“Naloxone.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/naloxone. Accessed 8 May. 2021.

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More Definitions for naloxone

naloxone

noun
nal·​ox·​one | \ nal-ˈäk-ˌsōn How to pronounce naloxone (audio) , ˈnal-ək-ˌsōn How to pronounce naloxone (audio) \

Medical Definition of naloxone

: a potent synthetic antagonist of narcotic drugs (as morphine and fentanyl) that is administered especially in the form of its hydrochloride C19H21NO4·HCl

Note: Naloxone is administered by injection or as a nasal spray to reverse the effects of opioids and especially in the emergency treatment of opioid overdose. It is also administered in combination with buprenorphine in the form of a dissolvable tablet placed under the tongue or a film placed inside the cheek to treat opioid dependence. Trademarks for preparations containing naloxone include Bunavail, Evzio, Narcan, Suboxone, and Zubsolv.

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