endotoxin

noun
en·​do·​tox·​in | \ ˌen-dō-ˈtäk-sən How to pronounce endotoxin (audio) \

Definition of endotoxin

: a toxic heat-stable lipopolysaccharide substance present in the outer membrane of gram-negative bacteria that is released from the cell upon lysis

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Other Words from endotoxin

endotoxic \ ˌen-​dō-​ˈtäk-​sik How to pronounce endotoxin (audio) \ adjective

Examples of endotoxin in a Sentence

Recent Examples on the Web The product is refined and sold as endotoxin test kits to pharmaceutical companies. Tim Prudente, baltimoresun.com, "How the coronavirus vaccine relies on Maryland’s strangest fishery: horseshoe crabs," 31 Dec. 2020 While other tests exist like synthetic LAL and a human blood test, LAL bacterial endotoxin testing is the gold standard, Hoffmeister said. Doug Fraser, USA TODAY, "Horseshoe crabs may be the answer to a safe coronavirus vaccine next year. Here's why.," 16 June 2020 Half were trained in the Method, then they all were injected with an endotoxin that caused fevers, chills, and headaches. Elizabeth Gulino, refinery29.com, "Is The Goop Lab Right About The Healing Powers Of Ice Water Baths?," 27 Jan. 2020 Scientists like Thurman and those from Lonza use horseshoe crab blood to test for the presence of potentially lethal endotoxins. Maddy Lauria, baltimoresun.com, "Using synthetic crab blood substitute in biomedical testing could help save horseshoe crabs and shorebirds," 22 June 2019 Gram-negative bacteria like E. coli contain a type of sugar called an endotoxin in their cell walls, while Gram-positive types like Staphylococcus (of the Staph infection) do not. Caren Chesler, Popular Mechanics, "The Blood of the Crab," 23 Aug. 2019 For Tammy Thurman, a senior scientist with Pfizer, visits to Pickering Beach have inspired her to look at the endotoxin testing made possible by crab blood in a bit of a different way. Maddy Lauria, baltimoresun.com, "Using synthetic crab blood substitute in biomedical testing could help save horseshoe crabs and shorebirds," 22 June 2019 The problem is that biomedical companies bleed the live crabs to use their blue blood in endotoxin tests — and as their numbers drop, so do the numbers of birds. Aaron Gilbreath, Longreads, "Will Big Pharma Help Save Some of the Oldest Marine Life on Earth?," 17 May 2018 And a few years ago, at an endotoxin summit in Delaware hosted by Lonza, Bolden witnessed the arrival of horseshoe crabs. Aaron Gilbreath, Longreads, "Will Big Pharma Help Save Some of the Oldest Marine Life on Earth?," 17 May 2018

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'endotoxin.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of endotoxin

1904, in the meaning defined above

History and Etymology for endotoxin

International Scientific Vocabulary

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Time Traveler for endotoxin

Time Traveler

The first known use of endotoxin was in 1904

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Last Updated

14 Jan 2021

Cite this Entry

“Endotoxin.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/endotoxin. Accessed 22 Jan. 2021.

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More Definitions for endotoxin

endotoxin

noun
en·​do·​tox·​in | \ ˌen-dō-ˈtäk-sən How to pronounce endotoxin (audio) \

Medical Definition of endotoxin

: a toxin of internal origin specifically : a poisonous substance present in bacteria (as the causative agent of typhoid fever) but separable from the cell body only on its disintegration — compare exotoxin

Other Words from endotoxin

endotoxic \ -​sik How to pronounce endotoxin (audio) \ adjective

More from Merriam-Webster on endotoxin

Britannica.com: Encyclopedia article about endotoxin

Comments on endotoxin

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