naloxone

noun

nal·​ox·​one na-ˈläk-ˌsōn How to pronounce naloxone (audio)
: a synthetic potent antagonist of narcotic drugs (such as morphine and fentanyl) that is administered especially in the form of its hydrochloride C19H21NO4·HCl

Note: Naloxone is administered by injection or as a nasal spray to reverse the effects of opioids especially in the emergency treatment of opioid overdose. It is also administered in combination with buprenorphine in the form of a dissolvable tablet placed under the tongue or a film placed inside the cheek to treat opioid dependence.

Examples of naloxone in a Sentence

Recent Examples on the Web In November, the Biden administration directed districts to have naloxone on hand and train students and employees on how and when to use it. Julia Coin, Charlotte Observer, 24 Jan. 2024 Those experiencing an overdose can have their lives saved if naloxone is administered in a timely fashion. Tony Holt, Arkansas Online, 25 Oct. 2023 The scientists will screen for five substances, including cocaine, fentanyl, methamphetamine, and xylazine, as well as the overdose treatment naloxone. Alice Park, Time, 21 Sep. 2023 An onlooker – even one without prior training – can successfully administer naloxone to an overdose victim within about a minute of a drone delivering the lifesaving opioid reversal agent. Nicole Adams, The Conversation, 22 Jan. 2024 Last January, Newsom released a state budget that included $3.5 million to purchase naloxone for every middle and high school in California. Christopher Tang and Thomas Choi, Twin Cities, 13 Jan. 2024 This week, city officials announced a partnership with the National Institute of Drug Abuse that will test wastewater for certain drugs, including fentanyl, methamphetamine and cocaine, as well as naloxone, the opioid reversal medication most commonly known by its brand name, Narcan. Grace Toohey, Los Angeles Times, 16 Dec. 2023 The average out-of-pocket cost of naloxone soared from $35 in 2014 to $250 in 2018. Andrew Van Dam, Washington Post, 6 Oct. 2023 Reid said all high schools and buses are equipped with naloxone. Karina Elwood, Washington Post, 11 Jan. 2024 See More

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'naloxone.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History

Etymology

N-allyl + hydroxy- + -one

First Known Use

1964, in the meaning defined above

Time Traveler
The first known use of naloxone was in 1964

Dictionary Entries Near naloxone

Cite this Entry

“Naloxone.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/naloxone. Accessed 28 Feb. 2024.

Medical Definition

naloxone

noun
: a potent synthetic antagonist of narcotic drugs (as morphine and fentanyl) that is administered especially in the form of its hydrochloride C19H21NO4·HCl

Note: Naloxone is administered by injection or as a nasal spray to reverse the effects of opioids and especially in the emergency treatment of opioid overdose. It is also administered in combination with buprenorphine in the form of a dissolvable tablet placed under the tongue or a film placed inside the cheek to treat opioid dependence. Trademarks for preparations containing naloxone include Bunavail, Evzio, Narcan, Suboxone, and Zubsolv.

Last Updated: - Updated example sentences
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