naloxone

noun
nal·​ox·​one | \ na-ˈläk-ˌsōn How to pronounce naloxone (audio) \

Definition of naloxone

: a synthetic potent antagonist of narcotic drugs (such as morphine and fentanyl) that is administered especially in the form of its hydrochloride C19H21NO4·HCl

Note: Naloxone is administered by injection or as a nasal spray to reverse the effects of opioids especially in the emergency treatment of opioid overdose. It is also administered in combination with buprenorphine in the form of a dissolvable tablet placed under the tongue or a film placed inside the cheek to treat opioid dependence.

Examples of naloxone in a Sentence

Recent Examples on the Web

New Hampshire policy makers are seizing on any sign that their efforts, such as a push to get naloxone into citizens’ hands, are bearing fruit. Jon Kamp, WSJ, "Deaths Level Off—and Even Decline—in Some Opioid Hotspots," 31 Dec. 2018 States have handed out thousands of naloxone kits to first responders, schools, family members and drug users themselves. Carla K. Johnson, The Seattle Times, "Q&A: Feds tackle opioid epidemic, but is it helping?," 28 Jan. 2019 Ohio has trumpeted more than $1 billion spent on policy efforts, including expanding naloxone access and painkiller-abuse prevention. Jon Kamp, WSJ, "Deaths Level Off—and Even Decline—in Some Opioid Hotspots," 31 Dec. 2018 The tracking system, believed to be the first of its kind in California, collects the names and phone numbers of people who overdosed on opioids and who received the emergency overdose antidote naloxone from first responders. Catherine Ho, San Francisco Chronicle, "Marin says new opioid overdose tracking program shows progress," 11 May 2018 Several legislators in Puerto Rico have been trying for more than two years to pass a measure that would in part allow non-medical and non-emergency personnel to administer naloxone, which can reverse respiratory failures from opioid overdoses. Danica Coto, The Seattle Times, "Growing opioid crisis adds to Puerto Rico’s problems," 7 Jan. 2019 Law enforcement pursued a naked man running in the roadway, and administered the anti-overdose drug naloxone to a woman. Joseph Clark, cleveland.com, "Resident finds neighbor's drugs: Olmsted Township Police Blotter," 1 May 2018 Supporters believe broadening access to naloxone will help Maine combat a worsening opioid problem. Jon Kamp, WSJ, "Maine Lawmakers Clash With Governor Over Naloxone Access," 16 Apr. 2018 Specifically, that includes on-the-ground harm reduction measures, such as naloxone (which can reverse opioid overdoses) and fentanyl test strips, as well as basic education for people taking these drugs in both prescription and illicit contexts. Sarah Jacoby, SELF, "Fentanyl Now Officially Causes the Most Drug Overdose Deaths in the U.S.," 20 Dec. 2018

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'naloxone.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of naloxone

1964, in the meaning defined above

History and Etymology for naloxone

N-allyl + hydroxy- + -one

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Last Updated

17 Apr 2019

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The first known use of naloxone was in 1964

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More Definitions for naloxone

naloxone

noun
nal·​ox·​one | \ nal-ˈäk-ˌsōn How to pronounce naloxone (audio) , ˈnal-ək-ˌsōn How to pronounce naloxone (audio) \

Medical Definition of naloxone

: a potent synthetic antagonist of narcotic drugs (as morphine and fentanyl) that is administered especially in the form of its hydrochloride C19H21NO4·HCl

Note: Naloxone is typically administered by injection to reverse the effects of opioids and especially in the emergency treatment of opioid overdose. It is also administered in combination with buprenorphine in the form of a dissolvable tablet placed under the tongue or a film placed inside the cheek to treat opioid dependence. Trademarks for preparations containing naloxone include Bunavail, Evzio, Narcan, Suboxone, and Zubsolv.

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