naloxone

noun
nal·ox·one | \na-ˈläk-ˌsōn \

Definition of naloxone 

: a synthetic potent antagonist of narcotic drugs (such as morphine and fentanyl) that is administered especially in the form of its hydrochloride C19H21NO4·HCl

Note: Naloxone is administered by injection or as a nasal spray to reverse the effects of opioids especially in the emergency treatment of opioid overdose. It is also administered in combination with buprenorphine in the form of a dissolvable tablet placed under the tongue or a film placed inside the cheek to treat opioid dependence.

Examples of naloxone in a Sentence

Recent Examples on the Web

Narcan is the brand name for the medication naloxone. Megan Cassidy, SFChronicle.com, "Two Alameda County sheriff’s investigators survive potentially lethal fentanyl exposure," 26 June 2018 And the bill does not include a requirement that the overdose-reversal drug naloxone be co-prescribed with opioids, an increasingly popular concept for pain patients viewed as at high overdose risk. 2. Lev Facher, STAT, "What’s in the House’s bills to address the opioid crisis — and what’s not," 21 June 2018 Drug company Pfizer this week issued a nationwide recall of two batches of naloxone, a drug used to treat opioid overdoses. Grace Donnelly, Fortune, "Pfizer Recall of Opioid Overdose Drug is the Latest in a Series of Shortages and Backorders," 6 June 2018 State and local governments have halted the rise in opioid deaths by improving access to naloxone, the drug that stops overdoses. Andy Marso, kansascity, "Overdoses, prison, scant treatment: Mother's story shows state of KC’s opioid crisis," 26 June 2018 And just last week, the U.S. surgeon general issued a rare nationwide advisory urging Americans to keep the opioid overdose antidote naloxone on hand. Molly Harbarger, OregonLive.com, "Portland VA study says that patients have same long-term pain with or without opioids," 11 Apr. 2018 Those who receive naloxone on multiple occasions have a 65 percent increase in their risk of death. Shari Rudavsky, Indianapolis Star, "Opioid overdose visits soar nearly 70% at Midwest emergency rooms, up 35% in Indiana," 7 Mar. 2018 In both cases, naloxone was administered and the patients were taken to Howard County General Hospital, police said. Jess Nocera, Howard County Times, "Fatal overdoses down in Howard County from last year," 10 July 2018 Previously, organizations needed a prescription from an individual physician in order to distribute naloxone. Catherine Ho, SFChronicle.com, "More California pharmacies to distribute opioid overdose drug," 6 July 2018

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'naloxone.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of naloxone

1964, in the meaning defined above

History and Etymology for naloxone

N-allyl + hydroxy- + -one

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Statistics for naloxone

Last Updated

16 Oct 2018

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The first known use of naloxone was in 1964

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More Definitions for naloxone

naloxone

noun
nal·ox·one | \nal-ˈäk-ˌsōn, ˈnal-ək-ˌsōn \

Medical Definition of naloxone 

: a potent synthetic antagonist of narcotic drugs (as morphine and fentanyl) that is administered especially in the form of its hydrochloride C19H21NO4·HCl

Note: Naloxone is typically administered by injection to reverse the effects of opioids and especially in the emergency treatment of opioid overdose. It is also administered in combination with buprenorphine in the form of a dissolvable tablet placed under the tongue or a film placed inside the cheek to treat opioid dependence. Trademarks for preparations containing naloxone include Bunavail, Evzio, Narcan, Suboxone, and Zubsolv.

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