molecule

noun

mol·​e·​cule ˈmä-li-ˌkyül How to pronounce molecule (audio)
Synonyms of moleculenext
1
: the smallest particle of a substance that retains all the properties (see property sense 1a) of the substance and is composed of one or more atoms (see atom sense 1a)
a molecule of water
a molecule of oxygen
2
: a tiny bit : particle
There is a molecule of evidence to support these charges.

Examples of molecule in a Sentence

There is not a molecule of evidence to support these charges. not a molecule of sense in that girl
Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
The light triggered a chemical rearrangement inside the crystal, reshaping its internal architecture and creating tiny cavities capable of trapping water molecules from the air. Neetika Walter, Interesting Engineering, 12 May 2026 Jet fuel and diesel are both classified as middle distillates and rely on the same portion of crude molecules. CNBC, 12 May 2026 Under oxidative stress, harmful molecules called reactive oxygen species (ROS) directly damage cellular DNA, causing cells to age prematurely. Md Published, Verywell Health, 11 May 2026 Since then, scientists have devised ways of redesigning these molecules to better infiltrate muscle cells, leading to vastly higher dystrophin levels. Jason Mast, STAT, 7 May 2026 See All Example Sentences for molecule

Word History

Etymology

French molécule, from New Latin molecula, diminutive of Latin moles mass

First Known Use

1701, in the meaning defined at sense 1

Time Traveler
The first known use of molecule was in 1701

Browse Nearby Words

Cite this Entry

“Molecule.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/molecule. Accessed 19 May. 2026.

Kids Definition

molecule

noun
mol·​e·​cule ˈmäl-i-ˌkyü(ə)l How to pronounce molecule (audio)
1
: the smallest particle of a substance having all the characteristics of the substance
a molecule of water
a molecule of oxygen
2
: a very small bit : particle

Medical Definition

molecule

noun
mol·​e·​cule ˈmäl-i-ˌkyü(ə)l How to pronounce molecule (audio)
: the smallest particle of a substance that retains all the properties of the substance and is composed of one or more atoms

More from Merriam-Webster on molecule

Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!

More from Merriam-Webster