molecule

noun

mol·​e·​cule ˈmä-li-ˌkyül How to pronounce molecule (audio)
1
: the smallest particle of a substance that retains all the properties (see property sense 1a) of the substance and is composed of one or more atoms (see atom sense 1a)
a molecule of water
a molecule of oxygen
2
: a tiny bit : particle
a molecule of political honestyTime

Examples of molecule in a Sentence

There is not a molecule of evidence to support these charges. not a molecule of sense in that girl
Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Crucially, the McG cycle links with the Calvin cycle, allowing the two systems to balance out excess molecules. Aamir Khollam, Interesting Engineering, 13 Sep. 2025 From cracks near its south pole, the moon blasts towering geysers of water vapor, ice and organic molecules into space, which are tantalizing hints of a hidden ocean that could, in theory, be habitable. Sharmila Kuthunur, Space.com, 12 Sep. 2025 Then, in the late 1860s, the chemist Friedrich Miescher identified the molecule DNA, eventually leading to the unraveling of its structure by Rosalind Franklin, James Watson, and Francis Crick in 1953. Alan Lightman september 12, Literary Hub, 12 Sep. 2025 In the Calvin cycle of photosynthesis, that reaction involves linking the carbon dioxide as part of a reaction that breaks apart a modified five-carbon sugar, creating two three-carbon molecules. ArsTechnica, 12 Sep. 2025 See All Example Sentences for molecule

Word History

Etymology

French molécule, from New Latin molecula, diminutive of Latin moles mass

First Known Use

1701, in the meaning defined at sense 1

Time Traveler
The first known use of molecule was in 1701

Browse Nearby Words

Cite this Entry

“Molecule.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/molecule. Accessed 17 Sep. 2025.

Kids Definition

molecule

noun
mol·​e·​cule ˈmäl-i-ˌkyü(ə)l How to pronounce molecule (audio)
1
: the smallest particle of a substance having all the characteristics of the substance
a molecule of water
a molecule of oxygen
2
: a very small bit : particle

Medical Definition

molecule

noun
mol·​e·​cule ˈmäl-i-ˌkyü(ə)l How to pronounce molecule (audio)
: the smallest particle of a substance that retains all the properties of the substance and is composed of one or more atoms

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